盐酸非索非那定

Description

Fexofenadine HCl · CAS 153439-40-8 · C32H40ClNO4. UNII 2S068B75ZU.

Identification

CAS Registry Number	153439-40-8
PubChem CID	63002
Molecular formula	C32H40ClNO4
IUPAC name	2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid;hydrochloride
UNII (FDA)	2S068B75ZU

Computed Descriptors

Molecular Weight	538.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	537.2645865
Monoisotopic Mass	537.2645865
Topological Polar Surface Area	81
Heavy Atom Count	38
Formal Charge	0
Complexity	678

Physical description & handling notes

• 71.8 [ug/mL] (The mean of the results at pH 7.4)

Regulatory Status

GHS notification summary	14.3% (1 / 7)

GHS Hazard Classification

GHS notification summary	14.3% (1 / 7)
Reported hazard statements	H302 (28.6%), H312 (14.3%), H315 (28.6%), H317 (42.9%), H319 (28.6%), H335 (14.3%), H360 (42.9%)

Documented Uses

• An antihistamine drug used in the treatment of hayfever and similar allergy symptoms.
• Breast Feeding; Lactation; Milk, Human; Antihistamines; Nonsedating Antihistamines
• Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)
• Histamine-1 Receptor Antagonist [EPC]; Histamine H1 Receptor Antagonists [MoA]
• Histamine H1 Receptor Antagonists [MoA]; Histamine-1 Receptor Antagonist [EPC]
• FEXOFENADINE HYDROCHLORIDE 180 MG

Synonyms

FEXOFENADINE HYDROCHLORIDE; 153439-40-8; FEXOFENADINE HCL; Allegra Allergy; Allegra Hives; MDL 16,455A; DTXSID5048716; Children's Allegra Hives; MDL-16455A; Children's Allegra Allergy; 2S068B75ZU; DTXCID2028642; Allergillic; IAllergy Relief; Children Allergy; Wal-fex

Frequently Asked Questions

What are the CAS number and molecular formula of Fexofenadine HCl?

CAS 153439-40-8; molecular formula C32H40ClNO4; molecular weight — g/mol.

What other names is Fexofenadine HCl known by?

FEXOFENADINE HYDROCHLORIDE, 153439-40-8, FEXOFENADINE HCL, Allegra Allergy, Allegra Hives, MDL 16,455A.

Is Fexofenadine HCl classified as hazardous?

14.3% of GHS notifications report no hazard classification (1 of 7).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.