菲戈替尼

Name: 菲戈替尼
Brand: 济南圣和化工有限公司

CAS 1206161-97-8C21H23N5O3SMW 425.5

菲戈替尼，CAS 登记号 1206161-97-8，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于有机化学品。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号1206161-97-8

分子式C21H23N5O3S

分子量425.5

LogP1.4

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域有机化学品

类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

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本页已列出菲戈替尼的 CAS 号：1206161-97-8，可与随货 COA 核对。

可以提供哪些规格和包装？

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菲戈替尼一般用在什么产品里？

主要涉及有机化学品。

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PubChem 公开数据

Description

Filgotinib · CAS 1206161-97-8 · C21H23N5O3S. UNII 3XVL385Q0M.

Identification

CAS Registry Number	1206161-97-8
PubChem CID	49831257
Molecular formula	C21H23N5O3S
IUPAC name	N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
UNII (FDA)	3XVL385Q0M

Computed Descriptors

Molecular Weight	425.5
XLogP3	1.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	425.15216079
Monoisotopic Mass	425.15216079
Topological Polar Surface Area	105
Heavy Atom Count	30
Formal Charge	0

Physical description & handling notes

In addition to targeted Janus kinase (JAK) 1 inhibition, filgotinib targets pro-inflammatory cytokine signalling by inhibiting IL-6 induced STAT1 phosphorylation. Serum C-reactive protein levels are also reduced in response to filgotinib administration.

GHS Hazard Classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (100%)

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

Documented Uses

Breast Feeding; Lactation; Milk, Human; Enzyme Inhibitors; Protein Kinase Inhibitors; Signal Transduction Inhibitors; Janus Kinase Inhibitors; JAK Inhibitors
L - Antineoplastic and immunomodulating agents
L04AF - Janus-associated kinase (jak) inhibitors
QL - Antineoplastic and immunomodulating agents
QL04AF - Janus-associated kinase (jak) inhibitors
Of the total administered dose of filgotinib, approximately 87% undergoes renal elimination while 15% undergoes faecal elimination.

Synonyms

Filgotinib; 1206161-97-8; GLPG-0634; 3XVL385Q0M; GS-6034 FREE BASE; GLPG 0634; G146034; G-146034; DTXSID80152935; filgotinibum; RefChem:921607; DTXCID7075426; 1206101-20-3; GLPG0634; Filgotinib (GLPG0634); N-(5-(4-((1,1-dioxidothiomorpholino)methyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

Frequently Asked Questions

What are the CAS number and molecular formula of Filgotinib?

CAS 1206161-97-8; molecular formula C21H23N5O3S; molecular weight — g/mol.

What other names is Filgotinib known by?

Filgotinib, 1206161-97-8, GLPG-0634, 3XVL385Q0M, GS-6034 FREE BASE, GLPG 0634.

Is Filgotinib classified as hazardous?

Hazard statements reported: H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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