Fluorescein sodium

Description

Fluorescein sodium · CAS 518-47-8 · C20H10Na2O5. UNII 93X55PE38X. Color Additive Status: 74.1708; Color Additive Status: 74.2708; Color Additive Status: 74.3708.

Identification

CAS Registry Number	518-47-8
PubChem CID	10608
Molecular formula	C20H10Na2O5
IUPAC name	disodium;2-(3-oxido-6-oxoxanthen-9-yl)benzoate
UNII (FDA)	93X55PE38X

Computed Descriptors

Molecular Weight	376.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	376.03236198
Monoisotopic Mass	376.03236198
Topological Polar Surface Area	89.5
Heavy Atom Count	27
Formal Charge	0
Complexity	644

Physical & Chemical Properties

Color Additive Status	74.1708
Color Additive Status	74.2708
Color Additive Status	74.3708
Color Additive Status	82.1708

Physical description & handling notes

• Fluorescein, disodium salt is an orange-red to dark red powder. Water-soluble form of fluorescein. Odorless and almost tasteless. pH (5% solution) 7.8. May be sensitive to prolonged exposure to light and to heat.
• Wet Solid
• Orange-red hygroscopic solid; [Merck Index] Dark red powder; [Sigma-Aldrich MSDS]
• Orange-red powder
• Yellow powder
• Orange-brown powder

Regulatory Status

Regulatory & Food Contact	FDA Regulatory Status of Color Additives: Drugs, Cosmetics, Devices FDA Cumulative Estimated Daily Intake (CEDI): FCS CIR / INCI: Hair dyeing; Cosmetic colorant
GHS notification summary	87.1% (263 / 302)

GHS Hazard Classification

GHS notification summary	87.1% (263 / 302)
Reported hazard statements	H315 (10.6%), H319 (11.3%)

Documented Uses

• Textiles (Printing, Dyeing, or Finishing) [Category: Industry]
• Highly purified product is used in solution as a diagnostic aid for evaluating corneal trauma and for treating intraocular inflammation.
• Because of its intense fluorescence and /non-/biodegradability, it is in great demand for tracing the course of underground streams and of factory effluents and sewage sources that contaminate underground water supplies.
• As a marker for sea-rescue operations
• For more Uses (Complete) data for D&C Yellow No. 8 (9 total), please visit the HSDB record page.
• Cosmetics -> Hair dyeing; Cosmetic colorant

Synonyms

Fluorescein disodium salt; Soluble fluorescein; Sodium fluorescein; Uranin; Uranine WSS; Resorcinol phthalein sodium; Uranine Yellow; Ak-Fluor; Fluorescein, soluble; Ki202; Sodium fluoresceinate; Fluoresceinum natricum; 93X55PE38X; D&C Yellow No. 8; Funduscein-25; Ki202(1)

Frequently Asked Questions

What are the CAS number and molecular formula of Fluorescein sodium?

CAS 518-47-8; molecular formula C20H10Na2O5; molecular weight — g/mol.

What other names is Fluorescein sodium known by?

Fluorescein disodium salt, Soluble fluorescein, Sodium fluorescein, Uranin, Uranine WSS, Resorcinol phthalein sodium.

What is the regulatory status of Fluorescein sodium?

Documented regulatory listings: FDA Regulatory Status of Color Additives: Drugs, Cosmetics, Devices; FDA Cumulative Estimated Daily Intake (CEDI): FCS; CIR / INCI: Hair dyeing; Cosmetic colorant.

Is Fluorescein sodium classified as hazardous?

87.1% of GHS notifications report no hazard classification (263 of 302).

What are the key physical properties of Fluorescein sodium?

Color Additive Status: 74.1708; Color Additive Status: 74.2708; Color Additive Status: 74.3708; Color Additive Status: 82.1708.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.