fluspirilene

Description

fluspirilene · CAS 1841-19-6 · C29H31F2N3O. UNII C5QA4GLR9M. Melting Point: 187.5-190; Solubility: 10; Solubility: 1.67e-03 g/L.

Identification

CAS Registry Number	1841-19-6
PubChem CID	3396
Molecular formula	C29H31F2N3O
IUPAC name	8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
UNII (FDA)	C5QA4GLR9M

Computed Descriptors

Molecular Weight	475.6
XLogP3	5.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	7
Exact Mass	475.24351894
Monoisotopic Mass	475.24351894
Topological Polar Surface Area	35.6
Heavy Atom Count	35
Formal Charge	0

Physical & Chemical Properties

Melting Point	187.5-190
Solubility	10
Solubility	1.67e-03 g/L
LogP	5.86
Dissociation Constants	8.66
Dissociation Constants	7.7

Physical description & handling notes

• Solid

GHS Hazard Classification

Reported hazard statements	H301 (100%), H410 (100%)

Documented Uses

• Used for the treatment of schizophrenia.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• N05AG - Diphenylbutylpiperidine derivatives
• QN05AG - Diphenylbutylpiperidine derivatives

Synonyms

Fluspirilene; 1841-19-6; Redeptin; Imap; Fluspirileno; McN-JR-6218; 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; R 6218; Fluspirilenum; DTXSID7045152; R-6218; C5QA4GLR9M; 8-(4,4-Bis(p-fluorophenyl)butyl)-1-phenyl-1,3,8-triazaspiro-(4.5)decan-4-one; 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4,4-bis(4-fluorophenyl)butyl)-1-phenyl-; Spirodiflamine; DTXCID5025152

Frequently Asked Questions

What are the CAS number and molecular formula of fluspirilene?

CAS 1841-19-6; molecular formula C29H31F2N3O; molecular weight — g/mol.

What other names is fluspirilene known by?

Fluspirilene, 1841-19-6, Redeptin, Imap, Fluspirileno, McN-JR-6218.

Is fluspirilene classified as hazardous?

Hazard statements reported: H301, H410.

What are the key physical properties of fluspirilene?

Melting Point: 187.5-190; Solubility: 10; Solubility: 1.67e-03 g/L; LogP: 5.86.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.