Fomepizole

Description

Fomepizole · CAS 7554-65-6 · C4H6N2. UNII 83LCM6L2BY. Melting Point: 25; Melting Point: 25 °C; Solubility: 5.59e+02 g/L.

Identification

CAS Registry Number	7554-65-6
PubChem CID	3406
Molecular formula	C4H6N2
IUPAC name	4-methyl-1H-pyrazole
UNII (FDA)	83LCM6L2BY

Computed Descriptors

Molecular Weight	82.10
XLogP3	1.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	82.053098200
Monoisotopic Mass	82.053098200
Topological Polar Surface Area	28.7
Heavy Atom Count	6
Formal Charge	0

Physical & Chemical Properties

Melting Point	25
Melting Point	25 °C
Solubility	5.59e+02 g/L
LogP	0.9

Physical description & handling notes

• Solid

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (68.8%), H314 (68.8%), H315 (31.2%), H318 (69.5%), H319 (30.5%), H335 (30.5%)

Documented Uses

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Antizol is indicated as an antidote for ethylene glycol (such as antifreeze) or methanol poisoning, or for use in suspected ethylene glycol or methanol ingestion, either alone or in combination with hemodialysis
• Antidotes and other substances used in poisonings > Specific
• Parenteral - General injections - IV: 5 mg per mL in 20 mL ampoule (sulfate); 1 g per mL in 1.5 mL ampoule (base)
• Harmful effects of or exposure to noxious substances, chiefly nonmedicinal as to source, not elsewhere classified
• Avoid alcohol. Fomepizole reduces the metabolism of alcohol by alcohol dehydrogenase, and alcohol also reduces fomepizole metabolism and elimination.

Synonyms

4-Methylpyrazole; fomepizole; 7554-65-6; 1H-Pyrazole, 4-methyl-; Fomepizol; 4-Methylpyrazol; Fomepizolum; CHEBI:5141; 83LCM6L2BY; NSC-760365; DTXSID3040649; 4 Methylpyrazole; 4 Methylpyrazole Monohydrochloride; RefChem:58530; DTXCID1020649; V03AB34

Frequently Asked Questions

What are the CAS number and molecular formula of Fomepizole?

CAS 7554-65-6; molecular formula C4H6N2; molecular weight — g/mol.

What other names is Fomepizole known by?

4-Methylpyrazole, fomepizole, 7554-65-6, 1H-Pyrazole, 4-methyl-, Fomepizol, 4-Methylpyrazol.

Is Fomepizole classified as hazardous?

Hazard statements reported: H302, H312, H314, H315, H318.

What are the key physical properties of Fomepizole?

Melting Point: 25; Melting Point: 25 °C; Solubility: 5.59e+02 g/L; LogP: 0.9.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.