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gemifioxacin

CAS 175463-14-6C18H20FN5O4MW 389.4

gemifioxacin (CAS No. 175463-14-6) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number175463-14-6
Molecular FormulaC18H20FN5O4
Molecular Weight389.4
Melting Point235-237 °C
LogP2.3
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of gemifioxacin?

The CAS number of gemifioxacin is 175463-14-6.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of gemifioxacin?

Main applications include Organic Chemicals.

How do I buy gemifioxacin or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

gemifioxacin · CAS 175463-14-6 · C18H20FN5O4. UNII OKR68Y0E4T. Melting Point: 235-237 °C; Solubility: 2.10e-01 g/L; LogP: 2.3.

Identification

CAS Registry Number175463-14-6
PubChem CID9571107
Molecular formulaC18H20FN5O4
IUPAC name7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
UNII (FDA)OKR68Y0E4T

Computed Descriptors

Molecular Weight389.4
XLogP3-0.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass389.14993230
Monoisotopic Mass389.14993230
Topological Polar Surface Area121
Heavy Atom Count28
Formal Charge0

Physical & Chemical Properties

Melting Point235-237 °C
Solubility2.10e-01 g/L
LogP2.3

Physical description & handling notes

  • Solid
  • Off-white, amorphous solid from chloroform-ethanol
  • Freely soluble at neutral pH (350 mg/mL at 37 °C, pH 7.0).
  • pKa1 = 6.4 /COOH/; pKa2 = 9.0 /NH2/
  • White to light brown solid. Freely soluble at neutral pH (350 ug/mL at 37 °C, pH 7.0) /Gemifloxacin mesylate/
  • Oral: Tablets, film-coated: 320 mg (of gemifloxacin) Factive (Oscient). /Gemifloxacin mesylate/

Documented Uses

  • Preparation: J. H. Kwak et al., EP 688772; C. Y. Hong et al., US 5633262 (1995, 1997 both to LG Chemical)
  • For the treatment of bacterial infection caused by susceptible strains such as S. pneumoniae, H. influenzae, H. parainfluenzae, or M. catarrhalis, S. pneumoniae (including multi-drug resistant strains [MDRSP]), M. pneumoniae, C. pneumoniae, or K. pneumoniae.
  • Gemifloxacin is a fourth generation, oral fluoroquinolone antibiotic used in the therapy of mild-to-moderate respiratory tract infections caused by susceptible organisms. Gemifloxacin has been linked to rare instances of acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Fluoroquinolones; Quinolones
  • Gemifloxacin is used for the treatment of acute bacterial exacerbation of chronic bronchitis caused by susceptible Streptococcus pneumoniae, Haemophilus influenzae, H. parainfluenzae, or Moraxella catarrhalis. /Included in US product label/
  • Gemifloxacin is used for the treatment of community-acquired pneumonia (CAP) of mild to moderate severity caused by susceptible S. pneumoniae (including multidrug-resistant strains), H. influenzae, M. catarrhalis, Mycoplasma pneumoniae, Chlamydophila pneumoniae (formerly Chlamydia pneumoniae), or Klebsiella pneumoniae. /Included in US product label/

Synonyms

Gemifloxacin; 175463-14-6; Factiv; Gemifloxacine; Gemifloxacino; SB 265805; LB-20304; OKR68Y0E4T; DTXSID3048495; CHEBI:101853; LB20304; Gemifloxacinum; RefChem:56635; DTXCID9028469; J01MA15; SB265805

Frequently Asked Questions

What are the CAS number and molecular formula of gemifioxacin?

CAS 175463-14-6; molecular formula C18H20FN5O4; molecular weight — g/mol.

What other names is gemifioxacin known by?

Gemifloxacin, 175463-14-6, Factiv, Gemifloxacine, Gemifloxacino, SB 265805.

What are the key physical properties of gemifioxacin?

Melting Point: 235-237 °C; Solubility: 2.10e-01 g/L; LogP: 2.3.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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