盐酸胍法辛

Description

Guanfacine hydrochloride · CAS 29110-48-3 · C9H10Cl3N3O. UNII PML56A160O. Ionization Efficiency: 3.65; Ionization Efficiency: 2.7; Ionization Efficiency: MeCN (80%).

Identification

CAS Registry Number	29110-48-3
PubChem CID	71401
Molecular formula	C9H10Cl3N3O
IUPAC name	N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride
UNII (FDA)	PML56A160O

Computed Descriptors

Molecular Weight	282.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	2
Exact Mass	280.988945
Monoisotopic Mass	280.988945
Topological Polar Surface Area	81.5
Heavy Atom Count	16
Formal Charge	0
Complexity	256

Physical & Chemical Properties

Ionization Efficiency	3.65
Ionization Efficiency	2.7
Ionization Efficiency	MeCN (80%)
Ionization Efficiency	DOI:10.1038/s41598-020-62573-z

Physical description & handling notes

• Positive
• Agilent XCT
• Electrospray ionization
• formic acid (5.3nM)

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic alpha-2 Receptor Agonists
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS.
• Central alpha-2 Adrenergic Agonist [EPC]; Adrenergic alpha2-Agonists [MoA]

Synonyms

guanfacine hydrochloride; 29110-48-3; GUANFACINE HCL; Intuniv; BS 100-141; SPD503; N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride; Guafacine hydrochloride; DTXSID2045157; BS-100-141; PML56A160O; Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride; DTXCID0025157; Gaunfacine; Akfen; Guanfacine ER

Frequently Asked Questions

What are the CAS number and molecular formula of Guanfacine hydrochloride?

CAS 29110-48-3; molecular formula C9H10Cl3N3O; molecular weight — g/mol.

What other names is Guanfacine hydrochloride known by?

guanfacine hydrochloride, 29110-48-3, GUANFACINE HCL, Intuniv, BS 100-141, SPD503.

Is Guanfacine hydrochloride classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of Guanfacine hydrochloride?

Ionization Efficiency: 3.65; Ionization Efficiency: 2.7; Ionization Efficiency: MeCN (80%); Ionization Efficiency: DOI:10.1038/s41598-020-62573-z.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.