Harmane

Description

Harmane · CAS 486-84-0 · C12H10N2. UNII 82D6J0535P. Melting Point: 237 - 238 °C; LogP: 3.10; LogP: 2.89.

Identification

CAS Registry Number	486-84-0
PubChem CID	5281404
Molecular formula	C12H10N2
IUPAC name	1-methyl-9H-pyrido[3,4-b]indole
UNII (FDA)	82D6J0535P

Computed Descriptors

Molecular Weight	182.22
XLogP3	3.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	182.084398327
Monoisotopic Mass	182.084398327
Topological Polar Surface Area	28.7
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	237 - 238 °C
LogP	3.10
LogP	2.89

Physical description & handling notes

• Solid
• 136.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 135.25 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 141.88 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	50% (1 / 2)

GHS Hazard Classification

GHS notification summary	50% (1 / 2)
Reported hazard statements	H302 (50%), H315 (50%)

Documented Uses

• Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
• Toxic substances from microorganisms, plants or animals that interfere with the functions of the nervous system. Most venoms contain neurotoxic substances. Myotoxins are included in this concept.

Synonyms

Harman; HARMANE; 486-84-0; 1-Methyl-9H-pyrido[3,4-b]indole; Aribine; Locuturine; Loturine; Aribin; Locuturin; Passiflorin; 1-Methylnorharman; 1-Methyl-beta-carboline; 9H-Pyrido[3,4-b]indole, 1-methyl-; 1-methyl-2-carboline; 9H-Pyrido(3,4-b)indole, 1-methyl-; 1-Methyl-9H-pyrido(3,4-b)indole

Frequently Asked Questions

What are the CAS number and molecular formula of Harmane?

CAS 486-84-0; molecular formula C12H10N2; molecular weight — g/mol.

What other names is Harmane known by?

Harman, HARMANE, 486-84-0, 1-Methyl-9H-pyrido[3,4-b]indole, Aribine, Locuturine.

Is Harmane classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

What are the key physical properties of Harmane?

Melting Point: 237 - 238 °C; LogP: 3.10; LogP: 2.89.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.