甲基溴后马托品

Description

Homatropine Methylbromide · CAS 80-49-9 · C17H24BrNO3. UNII 68JRS2HC1C. Melting Point: 191-192 °C; LogP: 3.421.

Identification

CAS Registry Number	80-49-9
PubChem CID	6646
Molecular formula	C17H24BrNO3
IUPAC name	(8,8-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl) 2-hydroxy-2-phenylacetate bromide
UNII (FDA)	68JRS2HC1C

Computed Descriptors

Molecular Weight	370.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	369.09396
Monoisotopic Mass	369.09396
Topological Polar Surface Area	46.5
Heavy Atom Count	22
Formal Charge	0
Complexity	373

Physical & Chemical Properties

Melting Point	191-192 °C
LogP	3.421

Physical description & handling notes

• Homatropine methylbromide belongs to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.

Regulatory Status

GHS notification summary	1.5% (1 / 66)

GHS Hazard Classification

GHS notification summary	1.5% (1 / 66)
Reported hazard statements	H302 (98.5%)

Documented Uses

• 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-: INACTIVE
• Used in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcers, gastric ulcers and duodenal ulcers, to reduce further gastric acid secretion and delay gastric emptying.
• A - Alimentary tract and metabolism
• A03 - Drugs for functional gastrointestinal disorders
• A03B - Belladonna and derivatives, plain
• A03BB - Belladonna alkaloids, semisynthetic, quaternary ammonium compounds

Synonyms

homatropine methylbromide; 80-49-9; Methylhomatropine bromide; Omatropina metilbromuro; 8-Methylhomatropinium bromide; Equipin; Tropinium methobromide mandelate; Methylhomatropinum bromatum; Homapin-5; Homatropini methylbromidum; Methylbromure d'homatropine; Metilbromuro de homatropina; Homapin-10; 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate; CHEBI:50373; 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide

Frequently Asked Questions

What are the CAS number and molecular formula of Homatropine Methylbromide?

CAS 80-49-9; molecular formula C17H24BrNO3; molecular weight — g/mol.

What other names is Homatropine Methylbromide known by?

homatropine methylbromide, 80-49-9, Methylhomatropine bromide, Omatropina metilbromuro, 8-Methylhomatropinium bromide, Equipin.

Is Homatropine Methylbromide classified as hazardous?

1.5% of GHS notifications report no hazard classification (1 of 66).

What are the key physical properties of Homatropine Methylbromide?

Melting Point: 191-192 °C; LogP: 3.421.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.