氢化可的松醋丙酯

Description

Hydrocortisone Aceponate · CAS 74050-20-7 · C26H36O7. UNII 2340UP1L2G.

Identification

CAS Registry Number	74050-20-7
PubChem CID	68921
Molecular formula	C26H36O7
IUPAC name	[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
UNII (FDA)	2340UP1L2G

Computed Descriptors

Molecular Weight	460.6
XLogP3	3.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	460.24610348
Monoisotopic Mass	460.24610348
Topological Polar Surface Area	107
Heavy Atom Count	33
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H360 (96%), H373 (96%)

Documented Uses

• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
• D07 - Corticosteroids, dermatological preparations
• D07AC - Corticosteroids, potent (group iii)
• D07AC16 - Hydrocortisone aceponate
• QD07 - Corticosteroids, dermatological preparations

Synonyms

Hydrocortisone aceponate; 74050-20-7; Efficort; Cortavance; Aceponate d'hydrocortisone; Aceponato de hidrocortisona; Hydrocortisoni aceponas; 2340UP1L2G; EASOTIC COMPONENT HYDROCORTISONE ACEPONATE; RefChem:55343; 21-(acetyloxy)-11beta-hydroxy-17alpha-(propionyloxy)-4-pregnene-3,20-dione; Hydrocortisone 17-Propionate 21-Acetate; Hydrocortisone aceponate [INN]; retef; Hydrocortisone aceponate (INN); Suniderma

Frequently Asked Questions

What are the CAS number and molecular formula of Hydrocortisone Aceponate?

CAS 74050-20-7; molecular formula C26H36O7; molecular weight — g/mol.

What other names is Hydrocortisone Aceponate known by?

Hydrocortisone aceponate, 74050-20-7, Efficort, Cortavance, Aceponate d'hydrocortisone, Aceponato de hidrocortisona.

Is Hydrocortisone Aceponate classified as hazardous?

Hazard statements reported: H360, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.