羟基氟他胺

Description

Hydroxyflutamide · CAS 52806-53-8 · C11H11F3N2O4. UNII 31D90UKP5Y. LogP: 2.7.

Identification

CAS Registry Number	52806-53-8
PubChem CID	91649
Molecular formula	C11H11F3N2O4
IUPAC name	2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
UNII (FDA)	31D90UKP5Y

Computed Descriptors

Molecular Weight	292.21
XLogP3	2.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	292.06709132
Monoisotopic Mass	292.06709132
Topological Polar Surface Area	95.2
Heavy Atom Count	20
Formal Charge	0

Physical & Chemical Properties

LogP	2.7

Physical description & handling notes

• 157.4 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8033562]

GHS Hazard Classification

Reported hazard statements	H302 (55.7%), H315 (45.5%), H319 (45.5%), H335 (44.3%), H360 (53.4%), H372 (53.4%), H411 (54.5%)

Documented Uses

• In men, antiandrogens are most frequently used to treat prostate cancer. In women, antiandrogens are used to decrease levels of male hormones causing symptoms of hyperandrogenism. (Wikipedia)
• Compounds which inhibit or antagonize the biosynthesis or actions of androgens.
• 2-hydroxy-flutamide is a known human metabolite of flutamide.

Synonyms

Hydroxyflutamide; 52806-53-8; 2-hydroxyflutamide; hydroxy-flutamide; 2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide; 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide; Sch 16423; OH-flutamide; Sch-16423; DTXSID8033562; Propanamide, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-; 31D90UKP5Y; DTXCID6013562; Propanamide, 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)-; alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro-m-lactotoluidide; RefChem:147185

Frequently Asked Questions

What are the CAS number and molecular formula of Hydroxyflutamide?

CAS 52806-53-8; molecular formula C11H11F3N2O4; molecular weight — g/mol.

What other names is Hydroxyflutamide known by?

Hydroxyflutamide, 52806-53-8, 2-hydroxyflutamide, hydroxy-flutamide, 2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide.

Is Hydroxyflutamide classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H360.

What are the key physical properties of Hydroxyflutamide?

LogP: 2.7.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.