咪达普利

Description

Imidapril · CAS 89371-37-9 · C20H27N3O6. UNII BW7H1TJS22.

Identification

CAS Registry Number	89371-37-9
PubChem CID	5464343
Molecular formula	C20H27N3O6
IUPAC name	(4S)-3-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-1-methyl-2-oxoimidazolidine-4-carboxylic acid
UNII (FDA)	BW7H1TJS22

Computed Descriptors

Molecular Weight	405.4
XLogP3	-0.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	10
Exact Mass	405.18998559
Monoisotopic Mass	405.18998559
Topological Polar Surface Area	116
Heavy Atom Count	29
Formal Charge	0

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents
• A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• C09 - Agents acting on the renin-angiotensin system
• QC09 - Agents acting on the renin-angiotensin system

Synonyms

imidapril; 89371-37-9; Imidaprilum; Hipertene; Tanatril; BW7H1TJS22; (S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid; DTXSID2048242; CHEBI:135654; RefChem:147954; DTXCID3028217; C09AA16; 1-methyl-3-(2-(N-(1-ethoxycarbonyl-3-phenylpropyl)amino)propionyl)-2-oxoimidazolidine-4-carboxylic acid; CHEMBL317094; Imidapril (INN); IMIDAPRIL [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Imidapril?

CAS 89371-37-9; molecular formula C20H27N3O6; molecular weight — g/mol.

What other names is Imidapril known by?

imidapril, 89371-37-9, Imidaprilum, Hipertene, Tanatril, BW7H1TJS22.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.