indoprofen

Description

indoprofen · CAS 31842-01-0 · C17H15NO3. UNII CPE46ZU14N. Melting Point: 208-210.

Identification

CAS Registry Number	31842-01-0
PubChem CID	3718
Molecular formula	C17H15NO3
IUPAC name	2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]propanoic acid
UNII (FDA)	CPE46ZU14N

Computed Descriptors

Molecular Weight	281.30
XLogP3	2.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	281.10519334
Monoisotopic Mass	281.10519334
Topological Polar Surface Area	57.6
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	208-210

Physical description & handling notes

• >42.2 [ug/mL] (The mean of the results at pH 7.4)
• 166.6 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 166.4 Ų [M+H]+ [CCS Type: TW]
• 165.28 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 166.75 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 163.83 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H301 (100%), H351 (100%)

Documented Uses

• Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
• M01 - Antiinflammatory and antirheumatic products
• M01A - Antiinflammatory and antirheumatic products, non-steroids
• M01AE - Propionic acid derivatives
• QM01 - Antiinflammatory and antirheumatic products
• QM01A - Antiinflammatory and antirheumatic products, non-steroids

Synonyms

indoprofen; 31842-01-0; Isindone; Reumofene; Flosin; Flosint; Indoprofene; Indoprofeno; Praxis; Bor-ind; Indoprofenum; K 4277; 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone; DTXSID5045831; p-(1-Oxo-2-isoindolinyl)hydratropic acid; CPE46ZU14N

Frequently Asked Questions

What are the CAS number and molecular formula of indoprofen?

CAS 31842-01-0; molecular formula C17H15NO3; molecular weight — g/mol.

What other names is indoprofen known by?

indoprofen, 31842-01-0, Isindone, Reumofene, Flosin, Flosint.

Is indoprofen classified as hazardous?

Hazard statements reported: H301, H351.

What are the key physical properties of indoprofen?

Melting Point: 208-210.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.