拉佐肽

Description

Larazotide · CAS 258818-34-7 · C32H55N9O10. UNII ZN3R5560ZV.

Identification

CAS Registry Number	258818-34-7
PubChem CID	9810532
Molecular formula	C32H55N9O10
IUPAC name	2-[[(2S)-1-[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
UNII (FDA)	ZN3R5560ZV

Computed Descriptors

Molecular Weight	725.8
XLogP3	-3.6
Hydrogen Bond Donor Count	9
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	21
Exact Mass	725.40718899
Monoisotopic Mass	725.40718899
Topological Polar Surface Area	301
Heavy Atom Count	51
Formal Charge	0

Documented Uses

• Investigated for use/treatment in autoimmune diseases, diabetes mellitus type 1, and gastrointestinal diseases and disorders (miscellaneous).
• AT-1001 is an orally administered octapeptide zonulin receptor antagonist that appears to exert its inhibitory effect on gliadin-induced tight junction disassembly by blocking putative zonulin receptors on the luminal surface of the small intestine.

Synonyms

Larazotide; 258818-34-7; Larazotida; Larazotide [USAN:INN]; AT-2347; AT 2347; ZN3R5560ZV; DTXSID30180526; glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine; larazotidum; Larazotide [INN]; RefChem:798506; LARAZOTIDE [USAN]; LARAZOTIDE [WHO-DD]; DTXCID70103017; Glycine, glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-

Frequently Asked Questions

What are the CAS number and molecular formula of Larazotide?

CAS 258818-34-7; molecular formula C32H55N9O10; molecular weight — g/mol.

What other names is Larazotide known by?

Larazotide, 258818-34-7, Larazotida, Larazotide [USAN:INN], AT-2347, AT 2347.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.