左西替利嗪

Description

Levocetirizine · CAS 130018-77-8 · C21H25ClN2O3. UNII 6U5EA9RT2O. Boiling Point: 542.1; Melting Point: 205-208.

Identification

CAS Registry Number	130018-77-8
PubChem CID	1549000
Molecular formula	C21H25ClN2O3
IUPAC name	2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
UNII (FDA)	6U5EA9RT2O

Computed Descriptors

Molecular Weight	388.9
XLogP3	1.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	388.1553704
Monoisotopic Mass	388.1553704
Topological Polar Surface Area	53
Heavy Atom Count	27
Formal Charge	0

Physical & Chemical Properties

Boiling Point	542.1
Melting Point	205-208

Documented Uses

• Use (kg; approx.) in Germany (2009): >100
• Consumption (g per capita; approx.) in Germany (2009): 0.00122
• Pharmaceuticals -> Antihistamines
• Levocetirizine is indicated to treat symptoms of perennial allergic rhinitis and uncomplicated skin manifestations of chronic idiopathic urticaria. It is also used over the counter for a variety of mild allergy symptoms.
• Breast Feeding; Lactation; Milk, Human; Antihistamines
• Cetirizine has known transformation products that include 4-Chlorobenzophenone, 1-[(4-Chlorophenyl)phenylmethyl]piperazine, and Cetirizine N-oxide.

Synonyms

Levocetirizine; 130018-77-8; (R)-cetirizine; (-)-Cetirizine; Xazal; Cetirizine, (r)-; Cetirizine, (-)-; Levocetirizina; 6U5EA9RT2O; Acetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-; 2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid; DTXSID60156294; 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid; levocetrizine; levocetirizinum; 2-(2-(4-((R)-(4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of Levocetirizine?

CAS 130018-77-8; molecular formula C21H25ClN2O3; molecular weight — g/mol.

What other names is Levocetirizine known by?

Levocetirizine, 130018-77-8, (R)-cetirizine, (-)-Cetirizine, Xazal, Cetirizine, (r)-.

What are the key physical properties of Levocetirizine?

Boiling Point: 542.1; Melting Point: 205-208.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.