Lidocaine

Description

Lidocaine · CAS 137-58-6 · C14H22N2O. UNII 98PI200987. Boiling Point: 159-160 °C at 2.00E+00 mm Hg; Boiling Point: BP: 180-182 °C at 4 mm Hg; 159-160 °C at 2 mm Hg; Boiling Point: 181 °C.

Identification

CAS Registry Number	137-58-6
PubChem CID	3676
Molecular formula	C14H22N2O
IUPAC name	2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide
UNII (FDA)	98PI200987

Computed Descriptors

Molecular Weight	234.34
XLogP3	2.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	234.173213330
Monoisotopic Mass	234.173213330
Topological Polar Surface Area	32.3
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

Boiling Point	159-160 °C at 2.00E+00 mm Hg
Boiling Point	BP: 180-182 °C at 4 mm Hg; 159-160 °C at 2 mm Hg
Boiling Point	181 °C
Melting Point	68.5
Melting Point	68 °C
Melting Point	68.5 °C
Solubility	4100
Solubility	In water, 410 mg/L at 30 °C
Solubility	5.93e-01 g/L
LogP	2.44

Physical description & handling notes

• Solid
• Needles from benzene or alcohol
• Yellow needles from water
• White or slightly yellow, crystalline powder
• Characteristic odor
• VERY SOL IN ALC; SOL IN CHLOROFORM; INSOL IN ETHER; WHITE CRYSTALLINE POWDER /LIDOCAINE HYDROCHLORIDE/

Regulatory Status

GHS notification summary	1.2% (2 / 167)

GHS Hazard Classification

GHS notification summary	1.2% (2 / 167)
Reported hazard statements	H302 (98.2%), H317, H362, H370, H372

Documented Uses

• THERAPEUTIC CATEGORY (VETERINARY): Anesthetic (local)
• Anesthetics, Local; Anti-Arrhythmia Agents; Voltage-Gated Sodium Channel Blockers
• Use (kg) in Switzerland (2009): >1000
• Use (kg; approx.) in Germany (2009): >7500
• Consumption (g per capita) in Switzerland (2009): 0.13
• Consumption (g per capita; approx.) in Germany (2009): 0.092

Synonyms

lidocaine; 137-58-6; Xylocaine; 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide; Duncaine; Lidoderm; Xylestesin; Esracaine; Gravocain; Isicaina; Leostesin; Maricaine; Solcain; Cappicaine; Solarcaine; Isicaine

Frequently Asked Questions

What are the CAS number and molecular formula of Lidocaine?

CAS 137-58-6; molecular formula C14H22N2O; molecular weight — g/mol.

What other names is Lidocaine known by?

lidocaine, 137-58-6, Xylocaine, 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide, Duncaine, Lidoderm.

Is Lidocaine classified as hazardous?

1.2% of GHS notifications report no hazard classification (2 of 167).

What are the key physical properties of Lidocaine?

Boiling Point: 159-160 °C at 2.00E+00 mm Hg; Boiling Point: BP: 180-182 °C at 4 mm Hg; 159-160 °C at 2 mm Hg; Boiling Point: 181 °C; Melting Point: 68.5.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.