(+/-)-薄荷醇

Description

(+/-)-Menthol · CAS 15356-70-4 · C10H20O. UNII L7T10EIP3A. Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 214.6 °C; Boiling Point: 214.00 to 216.00 °C. @ 760.00 mm Hg.

Identification

CAS Registry Number	15356-70-4
PubChem CID	1254
Molecular formula	C10H20O
IUPAC name	5-methyl-2-propan-2-ylcyclohexan-1-ol
UNII (FDA)	L7T10EIP3A
FEMA number	2665
JECFA number	427

Computed Descriptors

Molecular Weight	156.26
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	156.151415257
Monoisotopic Mass	156.151415257
Topological Polar Surface Area	20.2
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Boiling Point	421 °F at 760 mmHg (NTP, 1992)
Boiling Point	214.6 °C
Boiling Point	214.00 to 216.00 °C. @ 760.00 mm Hg
Boiling Point	212 °C ((-)-isomer 216.5)
Melting Point	100 °F (NTP, 1992)
Melting Point	-8 °C
Flash Point	196 °F (NTP, 1992)
Solubility	In water, 420 mg/L at 25 °C
Solubility	In water, 456 mg/L at 25 °C
Solubility	0.42 mg/mL at 25 °C

Physical description & handling notes

• D,l-menthol is a white crystalline solid with a peppermint odor and taste. (NTP, 1992)
• Liquid
• Other Solid; Liquid
• White solid with a cooling odor; [Hawley] Colorless solid with a peppermint odor; [HSDB] Colorless solid with a sweet odor; [MSDSonline]
• colourless, hexagonal crystals, usually needle-like; fused masses or crystalline powder with a pleasant, peppermint-like odour
• White crystals /89-78-1/

Regulatory Status

Regulatory & Food Contact	EU Flavoring substances FDA Substance added to food: FLAVORING AGENT OR ADJUVANT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent Mint, Cool JECFA ADI: 0-4 mg/kg bw
GHS notification summary	0.4% (7 / 1989)

GHS Hazard Classification

GHS notification summary	0.4% (7 / 1989)
Reported hazard statements	H315 (97.3%), H319 (82.9%), H318, H335, H402, H412

Documented Uses

• Painting (Solvents) [Category: Paint]
• Working with Glues and Adhesives [Category: Other]
• Using Disinfectants or Biocides [Category: Clean]
• Flavor in liquers, confectionary; perfumery, cigarettes, cough drops, and nasal inhalers. /L-Menthol/
• Because of its cooling and refreshing effect, (-)-menthol is used in large quantities in cigarettes, cosmetics, toothpastes, chewing gum, sweets, and medicines. /L-Menthol/
• Menthol, which provides a cooling sensation, is a common constituent of after-shaves.

Synonyms

MENTHOL; 1490-04-6; 2-Isopropyl-5-methylcyclohexanol; Menthyl alcohol; Mentholum; Caswell No. 540; Mineral ice; 5-Methyl-2-(1-methylethyl)cyclohexanol; 3-Hydroxy-p-menthane; 2-Isopropyl-5-methylcyclohexan-1-ol; CCRIS 9231; DTXSID8029650; EINECS 216-074-4; EPA Pesticide Chemical Code 051601; HSDB 593; AI3-08161

Frequently Asked Questions

What are the CAS number and molecular formula of (+/-)-Menthol?

CAS 15356-70-4; molecular formula C10H20O; molecular weight — g/mol.

What other names is (+/-)-Menthol known by?

MENTHOL, 1490-04-6, 2-Isopropyl-5-methylcyclohexanol, Menthyl alcohol, Mentholum, Caswell No. 540.

What is the regulatory status of (+/-)-Menthol?

Documented regulatory listings: EU Flavoring substances; FDA Substance added to food: FLAVORING AGENT OR ADJUVANT; Flavoring Agents.

Is (+/-)-Menthol classified as hazardous?

0.4% of GHS notifications report no hazard classification (7 of 1989).

What are the key physical properties of (+/-)-Menthol?

Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 214.6 °C; Boiling Point: 214.00 to 216.00 °C. @ 760.00 mm Hg; Boiling Point: 212 °C ((-)-isomer 216.5).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.