Mepivacaine

Description

Mepivacaine · CAS 22801-44-1 · C15H22N2O. UNII B6E06QE59J. Melting Point: 150.5; Melting Point: 150.5 °C; Solubility: 7000.

Identification

CAS Registry Number	22801-44-1
PubChem CID	4062
Molecular formula	C15H22N2O
IUPAC name	N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
UNII (FDA)	B6E06QE59J

Computed Descriptors

Molecular Weight	246.35
XLogP3	1.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	246.173213330
Monoisotopic Mass	246.173213330
Topological Polar Surface Area	32.3
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

Melting Point	150.5
Melting Point	150.5 °C
Solubility	7000
Solubility	6.21e-01 g/L
LogP	1.95
LogP	2.2
LogP	2.11
Dissociation Constants	7.7

Physical description & handling notes

• Solid
• 156.66 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 148.61 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 159.33 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 162.5 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 159.1 Ų [M+H]+ [CCS Type: TW; Method: Major Mix IMS/Tof Calibration Kit (Waters)]

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
• 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-: ACTIVE
• Breast Feeding; Lactation; Anesthetics, Local
• Mepivacaine (Class: Other Substances, Added Date: 02-2000)

Synonyms

mepivacaine; 96-88-8; N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide; DL-Mepivacaine; Scandicaine; Mepivacaina; Mepivacainum; tevacaine; 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-; Carboplyin Dental; 2',6'-Pipecoloxylidide, 1-methyl-; Mepisv; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide; (+-)-1-Methyl-2',6'-pipecoloxylidide; 1-METHYL-2',6'-PIPECOLOXYLIDIDE; B6E06QE59J

Frequently Asked Questions

What are the CAS number and molecular formula of Mepivacaine?

CAS 22801-44-1; molecular formula C15H22N2O; molecular weight — g/mol.

What other names is Mepivacaine known by?

mepivacaine, 96-88-8, N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide, DL-Mepivacaine, Scandicaine, Mepivacaina.

Is Mepivacaine classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of Mepivacaine?

Melting Point: 150.5; Melting Point: 150.5 °C; Solubility: 7000; Solubility: 6.21e-01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.