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Methylchloroisothiazolinone

CAS 26172-55-4C4H4ClNOSMW 148.97 g/mol

Methylchloroisothiazolinone (CAS No. 26172-55-4) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Cosmetic Raw Materials. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number26172-55-4
Molecular FormulaC4H4ClNOS
Molecular Weight148.97 g/mol
Melting Point54-55 °C
LogPlog Kow = 0.401 at 24 °C
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsCosmetic Raw Materials
CategoryCosmetic Raw Materials

Where it is used

Cosmetic Raw Materials

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Methylchloroisothiazolinone?

The CAS number of Methylchloroisothiazolinone is 26172-55-4.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Methylchloroisothiazolinone?

Main applications include Cosmetic Raw Materials.

How do I buy Methylchloroisothiazolinone or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Methylchloroisothiazolinone is identified by CAS 26172-55-4, molecular formula C4H4ClNOS and molecular weight 148.97 g/mol. UNII DEL7T5QRPN; ChEBI 53621; InChIKey DHNRXBZYEKSXIM-UHFFFAOYSA-N. Melting Point: 54-55 °C; Solubility: In water, 706-751 g/L at 20 °C; Vapor Pressure: 0.018 mm Hg at 25 °C.

Identification

CAS Registry Number26172-55-4
PubChem CID33344
Molecular formulaC4H4ClNOS
Molecular weight148.97 g/mol
IUPAC name5-chloro-2-methyl-1,2-thiazol-3-one
InChIKeyDHNRXBZYEKSXIM-UHFFFAOYSA-N
UNII (FDA)DEL7T5QRPN
ChEBI IDCHEBI:53621

Computed Descriptors

Molecular Weight149.60
XLogP30.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass148.9702126
Monoisotopic Mass148.9702126
Topological Polar Surface Area45.6
Heavy Atom Count8
Formal Charge0

Physical & Chemical Properties

Melting Point54-55 °C
SolubilityIn water, 706-751 g/L at 20 °C
Vapor Pressure0.018 mm Hg at 25 °C
LogPlog Kow = 0.401 at 24 °C

Physical description & handling notes

  • Liquid
  • Crystals from ligroin (60-90 °C)
  • Solubility in g/100 mL solvent: water, infinite
  • Solubility in g/100 mL solvent: ethyl acetate, 4.31; methanol, 4.40, toluene, 4.07; hexane, 0.28
  • In ethyl acetate, 38.06 g/L at 10 °C
  • For a mixture of 5-chloro-2-methyl-3(2H)-isothiazolone and 2-methyl-3(2H)-isothiazolone: Clear light amber liquid; density: 1.256 - 1.296 g/mL at 20-25 °C; viscosity: 11.4 cP at 25.7 °C

Regulatory Status

Regulatory & Food ContactFDA Cumulative Estimated Daily Intake (CEDI): FCS
FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
CIR / INCI: Cosmetic ingredients (Methylchloroisothiazolinone) -> CIR (Cosmetic Ingredient Review)
CIR / INCI: Preservative
GHS notification summary1.3% (31 / 2393)

GHS Hazard Classification

GHS notification summary1.3% (31 / 2393)
Reported hazard statementsH300 (20.2%), H301, H311 (24%), H310 (31.2%), H314 (98.3%), H317 (98.4%), H318 (64.9%), H330 (38.7%)

This chemical does not meet GHS hazard criteria for 1.3% (31 of 2393) of reports.

H300 (20.2%): Fatal if swallowed [Danger Acute toxicity, oral]

Documented Uses

  • CIR ingredient: Methylchloroisothiazolinone
  • Kathon preparations are used as preservatives in cosmetics and in many industrial applications: metalworking fluids, latex paints, adhesives, glues, developing solutions, and slime control agents in paper mills. [Marks, p. 102-4] Used as a preservative in leather processing; [PMID 21938525] Exposed workers include house painters, printers, housekeepers, and machinists.
  • Metal Machining [Category: Heat or Machine]
  • Semiconductor Manufacturing [Category: Industry]
  • Pulp and Paper Processing [Category: Industry]
  • Painting (Pigments, Binders, and Biocides) [Category: Paint]

Synonyms

5-Chloro-2-methyl-4-isothiazolin-3-one; 26172-55-4; Methylchloroisothiazolinone; CMIT; 5-Chloro-2-methyl-3(2H)-isothiazolone; 5-Chloro-2-methyl-3-isothiazolone; Kathon CG 5243; 3(2H)-Isothiazolone, 5-chloro-2-methyl-; 5-chloro-N-methylisothiazolone; 5-chloro-2-methylisothiazolin-3-one; 5-chloro-n-methylisothiazolin-3-one; HS 818; n-methyl-5-chloroisothiazolone; DEL7T5QRPN; DTXSID9034286; 4-ISOTHIAZOLIN-3-ONE, 5-CHLORO-2-METHYL-

Frequently Asked Questions

What are the CAS number and molecular formula of Methylchloroisothiazolinone?

CAS 26172-55-4; molecular formula C4H4ClNOS; molecular weight 148.97 g/mol.

What other names is Methylchloroisothiazolinone known by?

5-Chloro-2-methyl-4-isothiazolin-3-one, 26172-55-4, Methylchloroisothiazolinone, CMIT, 5-Chloro-2-methyl-3(2H)-isothiazolone, 5-Chloro-2-methyl-3-isothiazolone.

What is the regulatory status of Methylchloroisothiazolinone?

Documented regulatory listings: FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; CIR / INCI: Cosmetic ingredients (Methylchloroisothiazolinone) -> CIR (Cosmetic Ingredient Review).

Is Methylchloroisothiazolinone classified as hazardous?

1.3% of GHS notifications report no hazard classification (31 of 2393).

What are the key physical properties of Methylchloroisothiazolinone?

Melting Point: 54-55 °C; Solubility: In water, 706-751 g/L at 20 °C; Vapor Pressure: 0.018 mm Hg at 25 °C; LogP: log Kow = 0.401 at 24 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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