琥珀酸美托洛尔

Description

Metroprolol succinate · CAS 98418-47-4 · C34H56N2O10. UNII TH25PD4CCB.

Identification

CAS Registry Number	98418-47-4
PubChem CID	62937
Molecular formula	C34H56N2O10
IUPAC name	butanedioic acid;bis(1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol)
UNII (FDA)	TH25PD4CCB

Computed Descriptors

Molecular Weight	652.8
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	21
Exact Mass	652.39349599
Monoisotopic Mass	652.39349599
Topological Polar Surface Area	176
Heavy Atom Count	46
Formal Charge	0
Complexity	308

GHS Hazard Classification

Reported hazard statements	H302 (11.5%), H370 (75%), H412 (15.4%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic Beta-Antagonists; Antiarrhythmics
• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
• Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS.
• Adrenergic beta-Antagonists [MoA]; beta-Adrenergic Blocker [EPC]

Synonyms

Metoprolol succinate; 98418-47-4; Selozok; Toprol XL; Seloken-ZOK; Metoprolol hemisuccinate; H 93/26 succinate; TOPROL-XL; Toprol; DTXSID9048726; TH25PD4CCB; DTXCID6028652; KAPSPARGO; Metoprolol Succinate ER; RefChem:55626; KAPSPARGO SPRINKLE

Frequently Asked Questions

What are the CAS number and molecular formula of Metroprolol succinate?

CAS 98418-47-4; molecular formula C34H56N2O10; molecular weight — g/mol.

What other names is Metroprolol succinate known by?

Metoprolol succinate, 98418-47-4, Selozok, Toprol XL, Seloken-ZOK, Metoprolol hemisuccinate.

Is Metroprolol succinate classified as hazardous?

Hazard statements reported: H302, H370, H412.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.