Metsulfuron methyl

Description

Metsulfuron methyl · CAS 74223-64-6 · C14H15N5O6S. UNII 2589ET7417. Melting Point: 163 °C; Solubility: In water, 9.50X10+3 mg/L at 25 °C; Vapor Pressure: 0.000058 [mmHg].

Identification

CAS Registry Number	74223-64-6
PubChem CID	52999
Molecular formula	C14H15N5O6S
IUPAC name	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate
UNII (FDA)	2589ET7417

Computed Descriptors

Molecular Weight	381.37
XLogP3	1.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	6
Exact Mass	381.07430439
Monoisotopic Mass	381.07430439
Topological Polar Surface Area	158
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Melting Point	163 °C
Solubility	In water, 9.50X10+3 mg/L at 25 °C
Vapor Pressure	0.000058 [mmHg]
Vapor Pressure	2.5X10-12 mm Hg at 25 °C
LogP	log Kow = 2.20
LogP	0.93
Dissociation Constants	pKa = 3.8 at 20 °C

Physical description & handling notes

• White solid; [Merck Index] Colorless or white to pale yellow solid with a mild sweet ester-like odor; [HSDB]
• White crytals
• White to pale yellow solid
• Colorless crystals
• Faint, sweet, ester-like
• Solubility (mg/L at 25 °C): hexane 5.84X10-1, ethyl acetate 1.11X10+4, methanol 7.63X10+3, acetone 3.7X10+4, dichloromethane 1.32X10+5, toluene 1.24X10+3.

GHS Hazard Classification

Reported hazard statements	H400, H410

Documented Uses

• Used as pre- and post-emergence herbicide for control of broad-leaved weeds and annual grasses in barley, wheat, pastures, rangeland, and non-cropland; [HSDB]
• Postemergence for most broadleaf weeds, some annual grass weeds in barley, wheat, fallow, pastures, rangeland, and noncropland.
• Preparation ... G. Levitt, EP 7687 (1980 to DuPont); idem, US 4383113 (1983 to DuPont).
• Sulfonyl urea used as pre- and postemergence herbicide.
• Affects sensitive weeds through inhibition of the enzyme acetolactate synthase (ALS). Inhibition of ALS leads to the rapid cessation of cell division and subsequent growth processes in plants. Mode of action: Selective systemic herbicide absorbed through the roots and foliage and translocated to the apex of the plants. Symptoms appear within days, with death within 2-4 weeks.
• In mammals, following oral administration, metsulfuron-methyl is excreted predominantly unchanged. The methoxycarbonyl and sulfonylurea groups are only partly degraded, by O-demethylation and hydroxylation.

Synonyms

METSULFURON-METHYL; 74223-64-6; Metsulfuron methyl; Escort; Gropper; ALLY; Granstar; Allie; Metsulfuron methyl ester; Escort (pesticide); ALLY 20DF; HCHA 92HA; methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate; DTXSID6023864; DPD 63760H; DPX 6376

Frequently Asked Questions

What are the CAS number and molecular formula of Metsulfuron methyl?

CAS 74223-64-6; molecular formula C14H15N5O6S; molecular weight — g/mol.

What other names is Metsulfuron methyl known by?

METSULFURON-METHYL, 74223-64-6, Metsulfuron methyl, Escort, Gropper, ALLY.

Is Metsulfuron methyl classified as hazardous?

Hazard statements reported: H400, H410.

What are the key physical properties of Metsulfuron methyl?

Melting Point: 163 °C; Solubility: In water, 9.50X10+3 mg/L at 25 °C; Vapor Pressure: 0.000058 [mmHg]; Vapor Pressure: 2.5X10-12 mm Hg at 25 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.