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Description

Miconazole · CAS 22916-47-8 · C18H14Cl4N2O. UNII 7NNO0D7S5M. Melting Point: 170; Melting Point: 159 - 163 °C; Solubility: 7.63e-04 g/L.

Identification

CAS Registry Number	22916-47-8
PubChem CID	4189
Molecular formula	C18H14Cl4N2O
IUPAC name	1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
UNII (FDA)	7NNO0D7S5M

Computed Descriptors

Molecular Weight	416.1
XLogP3	5.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	415.983074
Monoisotopic Mass	413.986024
Topological Polar Surface Area	27.1
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	170
Melting Point	159 - 163 °C
Solubility	7.63e-04 g/L
LogP	6.1
LogP	5.81

Physical description & handling notes

• Solid
• 187.51 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	1% (1 / 104)

GHS Hazard Classification

GHS notification summary	1% (1 / 104)
Reported hazard statements	H302 (98.1%), H400 (54.8%), H410 (54.8%), H413 (39.4%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita; approx.) in Germany (2009): 0.0122
• For topical application in the treatment of tinea pedis (athlete&rsquo;s foot), tinea cruris, and tinea corporis caused by <i>Trichophyton rubrum</i>, <i>Trichophyton mentagrophytes</i>, and <i>Epidermophyton floccosum</i>, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
• Breast Feeding; Lactation; Milk, Human; Antifungal Agents; Dermatologic Agents
• Dermatological medicines > Antifungal medicines
• (1) Local - Topical - Cream: 2% (nitrate); (2) Local - Topical - Ointment: 2% (nitrate)

Synonyms

miconazole; 22916-47-8; Daktarin IV; Miconazol; Miconazolo; Miconazolum; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Daktarin; Oravig; 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole; DTXSID6023319; 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-; 7NNO0D7S5M; 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole; 1H-Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-; DTXCID803319

Frequently Asked Questions

What are the CAS number and molecular formula of Miconazole?

CAS 22916-47-8; molecular formula C18H14Cl4N2O; molecular weight — g/mol.

What other names is Miconazole known by?

miconazole, 22916-47-8, Daktarin IV, Miconazol, Miconazolo, Miconazolum.

Is Miconazole classified as hazardous?

1% of GHS notifications report no hazard classification (1 of 104).

What are the key physical properties of Miconazole?

Melting Point: 170; Melting Point: 159 - 163 °C; Solubility: 7.63e-04 g/L; LogP: 6.1.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.