尼伐地平

Description

nilvadipine · CAS 75530-68-6 · C19H19N3O6. UNII 0214FUT37J.

Identification

CAS Registry Number	75530-68-6
PubChem CID	4494
Molecular formula	C19H19N3O6
IUPAC name	3-O-methyl 5-O-propan-2-yl 2-cyano-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
UNII (FDA)	0214FUT37J

Computed Descriptors

Molecular Weight	385.4
XLogP3	2.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	6
Exact Mass	385.12738533
Monoisotopic Mass	385.12738533
Topological Polar Surface Area	134
Heavy Atom Count	28
Formal Charge	0

Physical description & handling notes

• Solid

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >50
• Consumption (g per capita; approx.) in Germany (2009): 0.000611
• For the management of vasospastic angina, chronic stable angina and hypertension.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• A class of drugs that act by selective inhibition of calcium influx through cellular membranes.
• C08C - Selective calcium channel blockers with mainly vascular effects

Synonyms

nilvadipine; 75530-68-6; Escor; Nivadil; Nivadipine; FR-34235; Nilvadipino; Nivadip; FK 235; Nilvadipinum; Dl-nilvadipine; FK-235; SK&F 102,362; CL 287,389; DTXSID2046624; SK&F-102362

Frequently Asked Questions

What are the CAS number and molecular formula of nilvadipine?

CAS 75530-68-6; molecular formula C19H19N3O6; molecular weight — g/mol.

What other names is nilvadipine known by?

nilvadipine, 75530-68-6, Escor, Nivadil, Nivadipine, FR-34235.

Is nilvadipine classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.