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Nolatrexed dihydrochloride

CAS 152946-68-4C14H14Cl2N4OSMW 357.3

Nolatrexed dihydrochloride (CAS No. 152946-68-4) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number152946-68-4
Molecular FormulaC14H14Cl2N4OS
Molecular Weight357.3
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsOrganic Chemicals
CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Nolatrexed dihydrochloride?

The CAS number of Nolatrexed dihydrochloride is 152946-68-4.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Nolatrexed dihydrochloride?

Main applications include Organic Chemicals.

How do I buy Nolatrexed dihydrochloride or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Nolatrexed dihydrochloride · CAS 152946-68-4 · C14H14Cl2N4OS. UNII 1XA69O733O.

Identification

CAS Registry Number152946-68-4
PubChem CID135409535
Molecular formulaC14H14Cl2N4OS
IUPAC name2-amino-6-methyl-5-pyridin-4-ylsulfanyl-3H-quinazolin-4-one;dihydrochloride
UNII (FDA)1XA69O733O

Computed Descriptors

Molecular Weight357.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass356.0265376
Monoisotopic Mass356.0265376
Topological Polar Surface Area106
Heavy Atom Count22
Formal Charge0
Complexity408

GHS Hazard Classification

Reported hazard statementsH341 (100%), H361 (97.9%)

H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

H361 (97.9%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Antimetabolites that are useful in cancer chemotherapy.
  • Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
  • Inhibitors of the enzyme, dihydrofolate reductase (TETRAHYDROFOLATE DEHYDROGENASE), which converts dihydrofolate (FH2) to tetrahydrofolate (FH4). They are frequently used in cancer chemotherapy. (From AMA, Drug Evaluations Annual, 1994, p2033)

Synonyms

Nolatrexed dihydrochloride; 152946-68-4; Thymitaq; AG 337; AG-337; DTXSID4046810; 1XA69O733O; AG337; 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)-, dihydrochloride; DTXCID2026810; 3,4-Dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)quinazoline dihydrochloride; Nolatrexed Hydrochloride; RefChem:927872; 3,4-dihydro-2-amino-6-methyl-4-oxy-5-(4-pyridylthio)-quinazoline dihydrochloride; Nolatrexed HCl; C14H14Cl2N4OS

Frequently Asked Questions

What are the CAS number and molecular formula of Nolatrexed dihydrochloride?

CAS 152946-68-4; molecular formula C14H14Cl2N4OS; molecular weight — g/mol.

What other names is Nolatrexed dihydrochloride known by?

Nolatrexed dihydrochloride, 152946-68-4, Thymitaq, AG 337, AG-337, DTXSID4046810.

Is Nolatrexed dihydrochloride classified as hazardous?

Hazard statements reported: H341, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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