醋酸奥曲肽

Description

Octreotide acetate · CAS 83150-76-9 · C49H66N10O10S2. UNII RWM8CCW8GP. Boiling Point: 1447; Melting Point: 153-156.

Identification

CAS Registry Number	83150-76-9
PubChem CID	448601
Molecular formula	C49H66N10O10S2
IUPAC name	(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
UNII (FDA)	RWM8CCW8GP

Computed Descriptors

Molecular Weight	1019.2
XLogP3	1
Hydrogen Bond Donor Count	13
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	17
Exact Mass	1018.44048069
Monoisotopic Mass	1018.44048069
Topological Polar Surface Area	383
Heavy Atom Count	71
Formal Charge	0

Physical & Chemical Properties

Boiling Point	1447
Melting Point	153-156

Documented Uses

• Consumption (g per capita) in the USA (2002): 2.86e-06
• Octreotide by injection is used for the treatment of acromegaly and the reduction of flushing and diarrhea symptoms related to carcinoid tumors and/or vasoactive intestinal peptide (VIPoma) tumors. The delayed-release oral formulation is used for the long-term treatment of acromegaly in patients who tolerate and respond adequately to injectable octreotide and [lanreotide].
• Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents, Hormonal; Gastrointestinal Agents
• Medicines for disorders of the pituitary hormone system
• (1) Parenteral - General injections - IM: 20 mg in vial (modified-release, as acetate) plus diluent; (2) Parenteral - General injections - SC: 0.05 mg per mL in 1 mL vial (immediate-release, as acetate); 0.1 mg per mL in 1 mL vial (immediate-release, as acetate); 0.5 mg per mL in 1 mL vial (immediate-release, as acetate)
• Acromegaly or pituitary gigantism

Synonyms

Octreotide; 83150-76-9; Octreotida; Octreotidum; RWM8CCW8GP; SMS-201-995; SMS995; SMS-995; DRG-0115; DTXSID0048682; CHEBI:7726; Compound 201995; Octreotide Acetate Salt; RefChem:59031; SMS 201995; Compound 201 995

Frequently Asked Questions

What are the CAS number and molecular formula of Octreotide acetate?

CAS 83150-76-9; molecular formula C49H66N10O10S2; molecular weight — g/mol.

What other names is Octreotide acetate known by?

Octreotide, 83150-76-9, Octreotida, Octreotidum, RWM8CCW8GP, SMS-201-995.

What are the key physical properties of Octreotide acetate?

Boiling Point: 1447; Melting Point: 153-156.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.