盐酸昂丹司琼

Description

Ondansetron HCL · CAS 99614-01-4 · C18H20ClN3O. UNII 2999F27MAD.

Identification

CAS Registry Number	99614-01-4
PubChem CID	68647
Molecular formula	C18H20ClN3O
IUPAC name	9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4-one;hydrochloride
UNII (FDA)	2999F27MAD

Computed Descriptors

Molecular Weight	329.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	329.1294900
Monoisotopic Mass	329.1294900
Topological Polar Surface Area	39.8
Heavy Atom Count	23
Formal Charge	0
Complexity	440

Physical description & handling notes

• 47.7 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H301 (98.8%), H318 (98.8%), H400 (98.8%), H410 (98.8%)

Documented Uses

• For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment of postoperative nausea and vomiting.
• Breast Feeding; Lactation; Milk, Human; Antiemetics; Gastrointestinal Agents; Serotonin Antagonists; Serotonin 5-HT3 Receptor Antagonists
• Ondansetron hydrochloride is approved to prevent:
• • Nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It is used in adults and children.
• Ondansetron hydrochloride is also being studied in the treatment of other conditions.
• Drugs used to prevent NAUSEA or VOMITING.

Synonyms

ONDANSETRON HYDROCHLORIDE; 99614-01-4; ONDANSETRON HCl; Zophren; NSC-665799; ZOFRAN PRESERVATIVE FREE; Ondansetron HCl dihydrate; 2999F27MAD; SN 307; NSC665799; Zofran and dextrose in plastic container; Ondansetron hydrochloride preservative free; DTXSID701027913; Setofilm; 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride; Ondansetron hydrochloride and dextrose in plastic container

Frequently Asked Questions

What are the CAS number and molecular formula of Ondansetron HCL?

CAS 99614-01-4; molecular formula C18H20ClN3O; molecular weight — g/mol.

What other names is Ondansetron HCL known by?

ONDANSETRON HYDROCHLORIDE, 99614-01-4, ONDANSETRON HCl, Zophren, NSC-665799, ZOFRAN PRESERVATIVE FREE.

Is Ondansetron HCL classified as hazardous?

Hazard statements reported: H301, H318, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.