磷酸奥司他韦

Description

Oseltamivir phosphate · CAS 204255-11-8 · C16H28N2O4. UNII 20O93L6F9H. Solubility: 6.86e-01 g/L; LogP: 1.21.

Identification

CAS Registry Number	204255-11-8
PubChem CID	65028
Molecular formula	C16H28N2O4
IUPAC name	ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate
UNII (FDA)	20O93L6F9H

Computed Descriptors

Molecular Weight	312.40
XLogP3	1.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	8
Exact Mass	312.20490738
Monoisotopic Mass	312.20490738
Topological Polar Surface Area	90.7
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Solubility	6.86e-01 g/L
LogP	1.21

Physical description & handling notes

• Solid
• Soluble
• pKa = 7.7 at 25 °C (primary amine)
• 180.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• Mol wt: 410.40. White crystalline solid /Phosphate/
• Oral: Capsules: 75 mg (of oseltamivir) (Tamiflu), (Roche); For Suspension: 12 mg (of oseltamivir) per mL (Tamiflu), (Roche). /Oseltamivir phosphate/

Documented Uses

• MEDICATION: Antiviral /Oseltamivir phosphate/
• Antiviral Agents; Enzyme Inhibitors
• Use (kg) in Switzerland (2009): >100
• Use (kg; approx.) in Germany (2009): >1000
• Consumption (g per capita) in Switzerland (2009): 0.013
• Consumption (g per capita; approx.) in Germany (2009): 0.012

Synonyms

oseltamivir; 196618-13-0; Tamvir; (-)-oseltamivir; GS-4104; ebilfumin; oseltamivirum; GS 4104; GS4104; HSDB 7433; Ro-640796; ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate; Ro-64-0796; Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate; Ro 640796; GS-4071 ETHYL ESTER

Frequently Asked Questions

What are the CAS number and molecular formula of Oseltamivir phosphate?

CAS 204255-11-8; molecular formula C16H28N2O4; molecular weight — g/mol.

What other names is Oseltamivir phosphate known by?

oseltamivir, 196618-13-0, Tamvir, (-)-oseltamivir, GS-4104, ebilfumin.

What are the key physical properties of Oseltamivir phosphate?

Solubility: 6.86e-01 g/L; LogP: 1.21.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.