盐酸帕洛诺司琼

Description

Palonosetron Hydrochloride · CAS 135729-62-3 · C19H25ClN2O. UNII 23310D4I19.

Identification

CAS Registry Number	135729-62-3
PubChem CID	6918303
Molecular formula	C19H25ClN2O
IUPAC name	(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride
UNII (FDA)	23310D4I19

Computed Descriptors

Molecular Weight	332.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	332.1655411
Monoisotopic Mass	332.1655411
Topological Polar Surface Area	23.6
Heavy Atom Count	23
Formal Charge	0
Complexity	456

Regulatory Status

GHS notification summary	54.5% (6 / 11)

GHS Hazard Classification

GHS notification summary	54.5% (6 / 11)
Reported hazard statements	H302 (45.5%), H312 (18.2%), H332 (36.4%), H351 (18.2%)

Documented Uses

• Aloxi (Palonosetron Hydrochloride)
• Palonosetron hydrochloride is approved in adults and children aged 1 month and older to prevent:
• • Nausea and vomiting caused by chemotherapy and nausea and vomiting after surgery.
• Drugs used to prevent NAUSEA or VOMITING.
• Drugs that bind to but do not activate SEROTONIN 5-HT3 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT3 RECEPTOR AGONISTS.
• Serotonin 3 Receptor Antagonists [MoA]; Serotonin-3 Receptor Antagonist [EPC]

Synonyms

Palonosetron hydrochloride; 135729-62-3; PALONOSETRON HCl; DTXSID8046610; RS-25259-197; Palonocetron hydrochloride; Palonosetron (as hydrochloride); RS 25259-197; 23310D4I19; DTXCID6026610; CHEBI:85157; AKYNZEO COMPONENT PALONOSETRON HYDROCHLORIDE; posfrea; Palonsetron hydrochloride; RefChem:56727; Aloxi

Frequently Asked Questions

What are the CAS number and molecular formula of Palonosetron Hydrochloride?

CAS 135729-62-3; molecular formula C19H25ClN2O; molecular weight — g/mol.

What other names is Palonosetron Hydrochloride known by?

Palonosetron hydrochloride, 135729-62-3, PALONOSETRON HCl, DTXSID8046610, RS-25259-197, Palonocetron hydrochloride.

Is Palonosetron Hydrochloride classified as hazardous?

54.5% of GHS notifications report no hazard classification (6 of 11).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.