甲磺酸酚妥拉明

Description

Phentolamine Mesylate · CAS 65-28-1 · C18H23N3O4S. UNII Y7543E5K9T.

Identification

CAS Registry Number	65-28-1
PubChem CID	91430
Molecular formula	C18H23N3O4S
IUPAC name	3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid
UNII (FDA)	Y7543E5K9T

Computed Descriptors

Molecular Weight	377.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	377.14092740
Monoisotopic Mass	377.14092740
Topological Polar Surface Area	111
Heavy Atom Count	26
Formal Charge	0
Complexity	456

Physical description & handling notes

• >56.6 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (95.2%), H315 (97.6%), H319 (97.6%), H332 (95.2%), H335 (92.9%)

Documented Uses

• Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
• Adrenergic alpha-Antagonists [MoA]; alpha-Adrenergic Blocker [EPC]

Synonyms

Phentolamine mesylate; 65-28-1; phentolamine mesilate; Phentolamine methanesulfonate; OraVerse; Mesylate phentolamine; RYZUMVI; NV-101; Y7543E5K9T; DTXSID60215315; Mesilate, Phentolamine; Mesylate, Phentolamine; RefChem:55851; Methanesulfonate, Phentolamine; DTXCID60137806; 2-(N-p'-Tolyl-N-(m'-hydroxyphenyl)aminomethyl)imidazoline Monomethanesulfonate

Frequently Asked Questions

What are the CAS number and molecular formula of Phentolamine Mesylate?

CAS 65-28-1; molecular formula C18H23N3O4S; molecular weight — g/mol.

What other names is Phentolamine Mesylate known by?

Phentolamine mesylate, 65-28-1, phentolamine mesilate, Phentolamine methanesulfonate, OraVerse, Mesylate phentolamine.

Is Phentolamine Mesylate classified as hazardous?

Hazard statements reported: H302, H312, H315, H319, H332.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.