Pindolol

Description

Pindolol · CAS 13523-86-9 · C14H20N2O2. UNII BJ4HF6IU1D. Melting Point: 171; Melting Point: 171-173 °C; Melting Point: 167 - 171 °C.

Identification

CAS Registry Number	13523-86-9
PubChem CID	4828
Molecular formula	C14H20N2O2
IUPAC name	1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
UNII (FDA)	BJ4HF6IU1D

Computed Descriptors

Molecular Weight	248.32
XLogP3	1.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	248.152477885
Monoisotopic Mass	248.152477885
Topological Polar Surface Area	57.3
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

Melting Point	171
Melting Point	171-173 °C
Melting Point	167 - 171 °C
Solubility	8.61e-01 g/L
LogP	1.75
LogP	log Kow = 1.75
LogP	1.9
LogP	1.76
Dissociation Constants	9.54
Dissociation Constants	9.25

Physical description & handling notes

• Solid
• Crystals from ethanol
• White to off-white crystalline powder
• Faint odor
• Practically Insoluble
• Practically insoluble in water and slightly soluble in alcohol

GHS Hazard Classification

Reported hazard statements	H302 (90.7%), H315 (93%), H319 (93%), H335 (93%), H301, H361, H362, H370

Documented Uses

• Use (kg; approx.) in Germany (2009): >10
• Consumption (g per capita; approx.) in Germany (2009): 0.000122
• Mixed beta-adrenergic blocker and serotonin 5HT1A-receptor antagonist.
• Pindolol is indicated in the management of hypertension. In Canada, it is also indicated in the prophylaxis of angina.
• Pindolol is a nonselective beta adrenergic receptor blocker that is widely used for the therapy of hypertension and angina pectoris. Pindolol has yet to be convincingly associated with clinically apparent liver injury.
• Breast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic Beta-Antagonists; Antiarrhythmics

Synonyms

pindolol; 13523-86-9; Visken; Prinodolol; Betapindol; Carvisken; Calvisken; Durapindol; Pinbetol; Decreten; Pectobloc; Pynastin; Blocklin L; LB-46; Glauco-visken; Blocklin-L

Frequently Asked Questions

What are the CAS number and molecular formula of Pindolol?

CAS 13523-86-9; molecular formula C14H20N2O2; molecular weight — g/mol.

What other names is Pindolol known by?

pindolol, 13523-86-9, Visken, Prinodolol, Betapindol, Carvisken.

Is Pindolol classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H301.

What are the key physical properties of Pindolol?

Melting Point: 171; Melting Point: 171-173 °C; Melting Point: 167 - 171 °C; Solubility: 8.61e-01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.