Piperazine dihydrochloride

Description

Piperazine dihydrochloride · CAS 142-64-3 · C4H10N2.2ClH. UNII 17VU4Z4W88. Melting Point: 635 °F (NIOSH, 2024); Melting Point: 635 °F; Solubility: 41 % (NIOSH, 2024).

Identification

CAS Registry Number	142-64-3
PubChem CID	8893
Molecular formula	C4H10N2.2ClH
IUPAC name	piperazine;dihydrochloride
UNII (FDA)	17VU4Z4W88

Computed Descriptors

Molecular Weight	159.05
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	158.0377538
Monoisotopic Mass	158.0377538
Topological Polar Surface Area	24.1
Heavy Atom Count	8
Formal Charge	0
Complexity	26.5

Physical & Chemical Properties

Melting Point	635 °F (NIOSH, 2024)
Melting Point	635 °F
Solubility	41 % (NIOSH, 2024)
Solubility	41%
Other Experimental Properties	82-83 °C /Monohydrate/

Physical description & handling notes

• Piperazine dihydrochloride appears as white to cream-colored needles or powder. Mp: 318-20 °C (with decomposition).
• White to cream-colored needles or powder; [NIOSH]
• White to cream-colored needles or powder.
• CREAM COLORED CRYSTALLINE POWDER
• WHITE NEEDLES
• White to creamy colored needles or powder.

Regulatory Status

Regulatory & Food Contact	FDA Substance added to food: Use unspecified

GHS Hazard Classification

Reported hazard statements	H315, H317, H319, H334, H412, H361 (92.9%), H303, H370

Documented Uses

• Used to manufacture fibers, pharmaceuticals, and insecticides; [ACGIH] Used as a veterinary anthelmintic medication and a curing agent for polychloroprene; [HSDB]
• Plastic Composites Manufacturing [Category: Industry]
• USED IN MAKING INSECTICIDES & FIBERS
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• CYCLIZATION OF ETHYLENEDIAMINE IN THE PRESENCE OF A METALLIC HYDROGENATION CATALYST, FOLLOWED BY REACTION WITH HYDROCHLORIC ACID
• ESSENTIALLY 100% FOR ANTHELMINTIC USE (1976)

Synonyms

Piperazine dihydrochloride; 142-64-3; Dowzene DHC; Piperazine, dihydrochloride; Piperazine wormer premix; Dihydro Pip Wormer; Diethylenediamine dihydrochloride; DTXSID4047096; Ascarex D; Dihydrochloride salt of diethylenediamine; 17VU4Z4W88; DTXCID2027096; Piperazine, hydrochloride (1:2); RefChem:58255; 205-551-2; piperazine;dihydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Piperazine dihydrochloride?

CAS 142-64-3; molecular formula C4H10N2.2ClH; molecular weight — g/mol.

What other names is Piperazine dihydrochloride known by?

Piperazine dihydrochloride, 142-64-3, Dowzene DHC, Piperazine, dihydrochloride, Piperazine wormer premix, Dihydro Pip Wormer.

What is the regulatory status of Piperazine dihydrochloride?

Documented regulatory listings: FDA Substance added to food: Use unspecified.

Is Piperazine dihydrochloride classified as hazardous?

Hazard statements reported: H315, H317, H319, H334, H412.

What are the key physical properties of Piperazine dihydrochloride?

Melting Point: 635 °F (NIOSH, 2024); Melting Point: 635 °F; Solubility: 41 % (NIOSH, 2024); Solubility: 41%.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.