马来酸丙氯拉嗪

Description

prochlorperazine dimaleate · CAS 84-02-6 · C28H32ClN3O8S. UNII I1T8O1JTL6.

Identification

CAS Registry Number	84-02-6
PubChem CID	5281032
Molecular formula	C28H32ClN3O8S
IUPAC name	bis((Z)-but-2-enedioic acid);2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
UNII (FDA)	I1T8O1JTL6

Computed Descriptors

Molecular Weight	606.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	8
Exact Mass	605.1598639
Monoisotopic Mass	605.1598639
Topological Polar Surface Area	184
Heavy Atom Count	41
Formal Charge	0
Complexity	548

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (93%), H332 (93%)

Documented Uses

• For the symptomatic management of psychotic disorders, short term management of nonpsychotic anxiety in patients with generalized anxiety disorder, and for the control of severe nausea and vomiting of various causes.
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Drugs used to prevent NAUSEA or VOMITING.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• Phenothiazines [CS]; Phenothiazine [EPC]
• Hepatic. Undergoes metabolism in the gastric mucosa and on first pass through the liver, CYP2D6 and/or CYP3A4. Half Life: 6 to 8 hours

Synonyms

Prochlorperazine dimaleate; Prochlorperazine maleate; 84-02-6; Proclorperazine maleate; Prochlorperazinu dimaleat; Prochlorperazine bimaleate; I1T8O1JTL6; Prochlorperazine hydrogen maleate; Prochloroproazine hydrogen maleate; 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, (Z)-2-butenedioate (1:2); 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine, dimaleate; 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine dimaleate; 2-Chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine dimaleate; CHEBI:8436; 10H-PHENOTHIAZINE, 2-CHLORO-10-(3-(4-METHYL-1-PIPERAZINYL)PROPYL)-, (2Z)-2-BUTENEDIOATE (1:2); NSC17478

Frequently Asked Questions

What are the CAS number and molecular formula of prochlorperazine dimaleate?

CAS 84-02-6; molecular formula C28H32ClN3O8S; molecular weight — g/mol.

What other names is prochlorperazine dimaleate known by?

Prochlorperazine dimaleate, Prochlorperazine maleate, 84-02-6, Proclorperazine maleate, Prochlorperazinu dimaleat, Prochlorperazine bimaleate.

Is prochlorperazine dimaleate classified as hazardous?

Hazard statements reported: H302, H312, H332.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.