proglumide

Description

proglumide · CAS 6620-60-6 · C18H26N2O4. UNII EPL8W5565D.

Identification

CAS Registry Number	6620-60-6
PubChem CID	4922
Molecular formula	C18H26N2O4
IUPAC name	4-benzamido-5-(dipropylamino)-5-oxopentanoic acid
UNII (FDA)	EPL8W5565D

Computed Descriptors

Molecular Weight	334.4
XLogP3	2.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	10
Exact Mass	334.18925731
Monoisotopic Mass	334.18925731
Topological Polar Surface Area	86.7
Heavy Atom Count	24
Formal Charge	0

Physical description & handling notes

• 181.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 186.48 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 183.95 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 175.76 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	100% (3 / 3)

GHS Hazard Classification

GHS notification summary	100% (3 / 3)

Documented Uses

• Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
• A - Alimentary tract and metabolism
• A02 - Drugs for acid related disorders
• A02B - Drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
• A02BX - Other drugs for peptic ulcer and gastro-oesophageal reflux disease (gord)
• QA - Alimentary tract and metabolism

Synonyms

proglumide; 6620-60-6; 4-benzamido-5-(dipropylamino)-5-oxopentanoic acid; Binoside; Xylamide; dl-proglumide; Milid; Nulsa; Gastrotopic; Midelid; Ulcutin; Proglumida; Xyde; Proglumidum; Promid; W-5219

Frequently Asked Questions

What are the CAS number and molecular formula of proglumide?

CAS 6620-60-6; molecular formula C18H26N2O4; molecular weight — g/mol.

What other names is proglumide known by?

proglumide, 6620-60-6, 4-benzamido-5-(dipropylamino)-5-oxopentanoic acid, Binoside, Xylamide, dl-proglumide.

Is proglumide classified as hazardous?

100% of GHS notifications report no hazard classification (3 of 3).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.