propantheline bromide

Description

propantheline bromide · CAS 50-34-0 · C23H30NO3.Br. UNII UX9Z118X9F. Melting Point: 318 to 322 °F (NTP, 1992).

Identification

CAS Registry Number	50-34-0
PubChem CID	9279
Molecular formula	C23H30NO3.Br
IUPAC name	methyl-di(propan-2-yl)-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium bromide
UNII (FDA)	UX9Z118X9F

Computed Descriptors

Molecular Weight	448.4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	447.14091
Monoisotopic Mass	447.14091
Topological Polar Surface Area	35.5
Heavy Atom Count	28
Formal Charge	0
Complexity	474

Physical & Chemical Properties

Melting Point	318 to 322 °F (NTP, 1992)

Physical description & handling notes

• Propantheline bromide appears as white crystals or white powder. Melting point 159-161 °C. Used therapeutically as an anticholinergic.
• greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
• >67.3 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statements	H302 (99.1%)

Documented Uses

• 2-Propanaminium, N-methyl-N-(1-methylethyl)-N-[2-[(9H-xanthen-9-ylcarbonyl)oxy]ethyl]-, bromide (1:1): INACTIVE
• Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
• Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system.

Synonyms

PROPANTHELINE BROMIDE; 50-34-0; Pro-Banthine; Neometantyl; Ercotina; Neopepulsan; Pantheline; Pervagal; Prodixamon; Propantel; Ercorax; Ketaman; Kivatin; Pantas; Pro-Gastron; Bromure de propantheline

Frequently Asked Questions

What are the CAS number and molecular formula of propantheline bromide?

CAS 50-34-0; molecular formula C23H30NO3.Br; molecular weight — g/mol.

What other names is propantheline bromide known by?

PROPANTHELINE BROMIDE, 50-34-0, Pro-Banthine, Neometantyl, Ercotina, Neopepulsan.

Is propantheline bromide classified as hazardous?

Hazard statements reported: H302.

What are the key physical properties of propantheline bromide?

Melting Point: 318 to 322 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.