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Relugolix

CAS 737789-87-6C29H27F2N7O5SMW 623.6

Relugolix (CAS No. 737789-87-6) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Pharmaceutical Intermediates & APIs. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number737789-87-6
Molecular FormulaC29H27F2N7O5S
Molecular Weight623.6
LogP1.69
Purity按批次COA提供(不公开发布)
Packaging按订单/批次确认(不公开发布)
ApplicationsPharmaceutical Intermediates & APIs
CategoryPharmaceutical Intermediates & APIs

Where it is used

Pharmaceutical Intermediates & APIs

Packaging & Supply

Packaging按订单/批次确认(不公开发布)
Purity按批次COA提供(不公开发布)
StorageSealed, cool and dry place
Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Relugolix?

The CAS number of Relugolix is 737789-87-6.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Relugolix?

Main applications include Pharmaceutical Intermediates & APIs.

How do I buy Relugolix or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Relugolix · CAS 737789-87-6 · C29H27F2N7O5S. UNII P76B05O5V6. LogP: 1.69.

Identification

CAS Registry Number737789-87-6
PubChem CID10348973
Molecular formulaC29H27F2N7O5S
IUPAC name1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
UNII (FDA)P76B05O5V6

Computed Descriptors

Molecular Weight623.6
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count11
Rotatable Bond Count9
Exact Mass623.17624448
Monoisotopic Mass623.17624448
Topological Polar Surface Area157
Heavy Atom Count44
Formal Charge0

Physical & Chemical Properties

LogP1.69

GHS Hazard Classification

Reported hazard statementsH360 (20%), H361 (60%), H371 (40%), H373 (20%), H411 (20%)

H360 (20%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H361 (60%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Documented Uses

  • Relugolix is indicated for the treatment of adult patients with advanced prostate cancer. In a combination product with [estradiol] and [norethindrone], relugolix is indicated for the once-daily treatment for the management of heavy menstrual bleeding associated with uterine fibroids in premenopausal women.
  • Relugolix is an orally administered, small molecule antagonist of gonadotropin releasing hormone (GnRH) that effectively blocks androgen production and is used to treat advanced prostate cancer. Relugolix therapy may be associated with a low rate of serum enzyme elevations during therapy, but has yet to be linked to instances of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Androgen Antagonists
  • Relugolix is approved to treat men with:
  • • Prostate cancer that is advanced.
  • Take with or without food. Administration with food does not result in any clinically meaningful differences in pharmacokinetics.

Synonyms

Relugolix; 737789-87-6; TAK-385; Orgovyx; TAK 385; TAK385; P76B05O5V6; DTXSID40224167; MYFEMBREE COMPONENT RELUGOLIX; relugolixum; RefChem:57784; DTXCID40146658; MFCD25976856; C29H27F2N7O5S; CHEMBL1800159; Relugolix [USAN:INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Relugolix?

CAS 737789-87-6; molecular formula C29H27F2N7O5S; molecular weight — g/mol.

What other names is Relugolix known by?

Relugolix, 737789-87-6, TAK-385, Orgovyx, TAK 385, TAK385.

Is Relugolix classified as hazardous?

Hazard statements reported: H360, H361, H371, H373, H411.

What are the key physical properties of Relugolix?

LogP: 1.69.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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