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瑞格列奈

CAS 135062-02-1C27H36N2O4MW 452.6

瑞格列奈,CAS 登记号 135062-02-1,由济南圣和化工有限公司现货供应,可提供纯度 按批次COA提供(不公开发布) 的规格,下游主要用于医药中间体及原料药。支持样品与小批量试用,批量价格请联系我们获取,验收以批次 COA 为准。

规格参数

CAS号135062-02-1
分子式C27H36N2O4
分子量452.6
熔点130-131 °C
LogP5.9
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域医药中间体及原料药
类别医药中间体及原料药

用途与场景

医药中间体及原料药

包装与供货

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
供货周期现货/按订单安排

文件与支持

每批随货提供 COA;可按需提供 MSDS 及技术文件。邮件注明产品名称与 CAS 号,一个工作日内回复报价。

常见问题

在哪里能查到 瑞格列奈 的 CAS 号?

本页已列出 瑞格列奈 的 CAS 号:135062-02-1,可与随货 COA 核对。

可以提供哪些规格和包装?

常见纯度为 按批次COA提供(不公开发布),包装形式为 按订单/批次确认(不公开发布),特殊规格可在询价时说明。

瑞格列奈 一般用在什么产品里?

主要涉及医药中间体及原料药。

下单流程是怎样的?

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PubChem 公开数据

Description

Repaglinide · CAS 135062-02-1 · C27H36N2O4. UNII 668Z8C33LU. Melting Point: 130-131 °C; Melting Point: 130 - 131 °C; Solubility: 2.94e-03 g/L.

Identification

CAS Registry Number135062-02-1
PubChem CID65981
Molecular formulaC27H36N2O4
IUPAC name2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid
UNII (FDA)668Z8C33LU

Computed Descriptors

Molecular Weight452.6
XLogP35.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Exact Mass452.26750763
Monoisotopic Mass452.26750763
Topological Polar Surface Area78.9
Heavy Atom Count33
Formal Charge0

Physical & Chemical Properties

Melting Point130-131 °C
Melting Point130 - 131 °C
Solubility2.94e-03 g/L
LogP5.9
LogP3.2
Dissociation Constants3.75

Physical description & handling notes

  • Solid
  • >67.9 [ug/mL] (The mean of the results at pH 7.4)

GHS Hazard Classification

Reported hazard statementsH361 (96.7%), H362 (98.3%), H412 (93.3%)

H361 (96.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

H362 (98.3%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]

Documented Uses

  • Use (kg; approx.) in Germany (2009): >100
  • Consumption (g per capita; approx.) in Germany (2009): 0.00122
  • As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
  • Repaglinide is a drug used in the treatment of diabetes mellitus type 2. It belongs to a class of antihyperglycemic agents known as meglitinides, along with nateglinide. Meglitinides work to reduce blood glucose levels by stimulating endogenous insulin production. The present recommended starting dose is dependent on hemoglobin A1c levels, with those below 8% (64 mmol/mol) urged to start with 0.5 mg pre-prandially and those above 8% to start with 1 to 2 mg.
  • Repaglinide is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically apparent acute liver injury.
  • Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents

Synonyms

Repaglinide; 135062-02-1; Prandin; Repaglinida; AG-EE 623 ZW; GlucoNorm; AG-EE 388 ZW; Repaglinidum; AGEE-623ZW; enyglid; AG-EE-623ZW; 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid; DTXSID3023552; NSC-759893; AG-EE-623-ZW; A10BX02

Frequently Asked Questions

What are the CAS number and molecular formula of Repaglinide?

CAS 135062-02-1; molecular formula C27H36N2O4; molecular weight — g/mol.

What other names is Repaglinide known by?

Repaglinide, 135062-02-1, Prandin, Repaglinida, AG-EE 623 ZW, GlucoNorm.

Is Repaglinide classified as hazardous?

Hazard statements reported: H361, H362, H412.

What are the key physical properties of Repaglinide?

Melting Point: 130-131 °C; Melting Point: 130 - 131 °C; Solubility: 2.94e-03 g/L; LogP: 5.9.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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