Revefenacin

Description

Revefenacin · CAS 864750-70-9 · C35H43N5O4. UNII G2AE2VE07O. Boiling Point: 777.5; Solubility: < 1 mg/ml; LogP: 3.22.

Identification

CAS Registry Number	864750-70-9
PubChem CID	11753673
Molecular formula	C35H43N5O4
IUPAC name	[1-[2-[[4-[(4-carbamoylpiperidin-1-yl)methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate
UNII (FDA)	G2AE2VE07O

Computed Descriptors

Molecular Weight	597.7
XLogP3	4.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	11
Exact Mass	597.33150487
Monoisotopic Mass	597.33150487
Topological Polar Surface Area	108
Heavy Atom Count	44
Formal Charge	0

Physical & Chemical Properties

Boiling Point	777.5
Solubility	< 1 mg/ml
LogP	3.22

GHS Hazard Classification

Reported hazard statements	H302 (100%), H312 (100%), H332 (100%)

Documented Uses

• Revefenacin is indicated as an inhalation solution for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD). COPD is a growing disease being the third leading cause of death in the US. This disease is characterized by not fully reversible airflow limitation.
• Revefenacin is a synthetic anticholinergic agent that is used as a once daily, nebulized inhalant for maintenance treatment of patients with chronic obstructive pulmonary disease. Revefenacin has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Parasympatholytics; Muscarinic Antagonists; Bronchodilator Agents
• Established Pharmacologic Class [EPC] - Anticholinergic
• Mechanisms of Action [MoA] - Cholinergic Antagonists
• Revefenacin is an Anticholinergic. The mechanism of action of revefenacin is as a Cholinergic Antagonist.

Synonyms

Revefenacin; 864750-70-9; TD-4208; Yupelri; GSK-1160724; revefenacina; revefenacine; GSK1160724; G2AE2VE07O; DTXSID701027775; revefenacinum; RefChem:57759; R03BB08; DTXCID801513351; Revefenacin [INN]; Revefenacin [WHO-DD]

Frequently Asked Questions

What are the CAS number and molecular formula of Revefenacin?

CAS 864750-70-9; molecular formula C35H43N5O4; molecular weight — g/mol.

What other names is Revefenacin known by?

Revefenacin, 864750-70-9, TD-4208, Yupelri, GSK-1160724, revefenacina.

Is Revefenacin classified as hazardous?

Hazard statements reported: H302, H312, H332.

What are the key physical properties of Revefenacin?

Boiling Point: 777.5; Solubility: < 1 mg/ml; LogP: 3.22.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.