Rimantadine

Description

Rimantadine · CAS 13392-28-4 · C12H21N. UNII 0T2EF4JQTU. Melting Point: >300 °C; Melting Point: > 300 °C; Solubility: 9.15e-03 g/L.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• Hydrochloride salt freely soluble (50 mg/ml at 20 °C)
• 145.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• White to off-white crystalline powder. MP: 373-375 °C; Solubility in water, 50 mg/L at 20 °C. /Hydrochloride/
• Oral: Solution: 50 mg/5 mL Flumadine Syrup ( with parabens) (Forest) Tablets, film-coated: 100 mg Flumadine ( with polyethylene glycol) (Forest).
• Formulated as the hydrochloride salt

Documented Uses

• Antiviral; Nucleic Acid Synthesis Inhibitors
• Netherlands 6408505; W.W. Prichard, US 3352912 (1965, 1967 both to duPont).
• For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults.
• Rimantadine is an antiviral agent used as therapy for influenza A. Rimantadine has not been associated with clinically apparent liver injury.
• Breast Feeding; Lactation; Antiviral Agents; Nucleic Acid Synthesis Inhibitors
• Rimantadine is indicated for the prophylaxis of respiratory tract infections caused by influenza A virus in adults and children, and the treatment of respiratory tract infections caused by influenza A virus in adults./Included in US product labeling/

Synonyms

rimantadine; 13392-28-4; Rimantadina; 1-(adamantan-1-yl)ethan-1-amine; Rimantadinum; Remantadine; alpha-Methyl-1-adamantanemethylamine; alpha-Methyladamantanemethylamine; 1-(1-Adamantyl)ethylamin; HSDB 7438; 0T2EF4JQTU; DTXSID2023561; Tricyclo(3.3.1.1(sup 3,7))decane-1-methanamine, alpha-methyl-; Riamantadine; Tricyclo(3.3.1.13,7)decane-1-methanamine, alpha-methyl-; J05AC02

Frequently Asked Questions

What are the CAS number and molecular formula of Rimantadine?

CAS 13392-28-4; molecular formula C12H21N; molecular weight — g/mol.

What other names is Rimantadine known by?

rimantadine, 13392-28-4, Rimantadina, 1-(adamantan-1-yl)ethan-1-amine, Rimantadinum, Remantadine.

What are the key physical properties of Rimantadine?

Melting Point: >300 °C; Melting Point: > 300 °C; Solubility: 9.15e-03 g/L; LogP: 3.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.