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Description

Roxadustat · CAS 808118-40-3 · C19H16N2O5. UNII X3O30D9YMX. Solubility: <1 mg/mL.

Identification

CAS Registry Number	808118-40-3
PubChem CID	11256664
Molecular formula	C19H16N2O5
IUPAC name	2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
UNII (FDA)	X3O30D9YMX

Computed Descriptors

Molecular Weight	352.3
XLogP3	3.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	352.10592162
Monoisotopic Mass	352.10592162
Topological Polar Surface Area	109
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Solubility	<1 mg/mL

GHS Hazard Classification

Reported hazard statements	H302 (66.7%), H315 (100%), H319 (100%), H332 (66.7%), H335 (100%)

Documented Uses

• Roxadustat is indicated for the treatment of adult patients with symptomatic anemia associated with chronic kidney disease (CKD).
• Take with or without food. Food can decrease Cmax but not to a clinically significant extent.
• B - Blood and blood forming organs
• B03X - Other antianemic preparations
• B03XA - Other antianemic preparations
• QB - Blood and blood forming organs

Synonyms

Roxadustat; 808118-40-3; FG-4592; FG4592; Evrenzo; ASP 1517; ASP1517; ASP-1517; X3O30D9YMX; roxadustatum; FG 4592; (((4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl)amino)acetic acid; CHEBI:132774; DTXSID60230644; N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine; [[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic Acid

Frequently Asked Questions

What are the CAS number and molecular formula of Roxadustat?

CAS 808118-40-3; molecular formula C19H16N2O5; molecular weight — g/mol.

What other names is Roxadustat known by?

Roxadustat, 808118-40-3, FG-4592, FG4592, Evrenzo, ASP 1517.

Is Roxadustat classified as hazardous?

Hazard statements reported: H302, H315, H319, H332, H335.

What are the key physical properties of Roxadustat?

Solubility: <1 mg/mL.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.