Setmelanotide

Name: Setmelanotide
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 920014-72-8C49H68N18O9S2MW 1117.3

Setmelanotide (CAS No. 920014-72-8) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number920014-72-8

Molecular FormulaC49H68N18O9S2

Molecular Weight1117.3

LogP-2.5

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsOrganic Chemicals

CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Setmelanotide?

The CAS number of Setmelanotide is 920014-72-8.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Setmelanotide?

Main applications include Organic Chemicals.

How do I buy Setmelanotide or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Setmelanotide · CAS 920014-72-8 · C49H68N18O9S2. UNII N7T15V1FUY.

Identification

CAS Registry Number	920014-72-8
PubChem CID	11993702
Molecular formula	C49H68N18O9S2
IUPAC name	(4R,7S,10S,13R,16S,19R,22R)-22-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]-13-benzyl-10-[3-(diaminomethylideneamino)propyl]-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-19-methyl-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexazacyclotricosane-4-carboxamide
UNII (FDA)	N7T15V1FUY

Computed Descriptors

Molecular Weight	1117.3
XLogP3	-2.5
Hydrogen Bond Donor Count	15
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	18
Exact Mass	1116.48580817
Monoisotopic Mass	1116.48580817
Topological Polar Surface Area	500
Heavy Atom Count	78
Formal Charge	0

Documented Uses

Setmelanotide is the first available anorexigenic agent, a melanocortin-4 receptor (MC4R) agonist for treating obesity caused by a rare genetic disorder. Setmelanotide was approved by the Food and Drug Administration (FDA) on November 25, 2020, for the indication of chronic weight management in adults and pediatrics six years of age and older due to the deficiency of proopiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency.
Setmelanotide is a melanocortin 4 receptor agonist that is used for chronic weight management for adults and children with rare genetic forms obesity due to gene defects in the melanocortin pathway. Setmelanotide therapy has not been associated serum aminotransferase or bilirubin elevations or to instances of clinically apparent liver injury.
Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents; Incretins; Glucagon-Like Peptide-1 Agonists; GLP-1 Agonists
Established Pharmacologic Class [EPC] - Melanocortin 4 Receptor Agonist
Mechanisms of Action [MoA] - Melanocortin 4 Receptor Agonists
Setmelanotide is a Melanocortin 4 Receptor Agonist. The mechanism of action of setmelanotide is as a Melanocortin 4 Receptor Agonist.

Synonyms

Setmelanotide; 920014-72-8; RM-493; BIM-22493; Setmelanotida; N7T15V1FUY; Setmelanotidum; DTXSID501032320; RefChem:58308; DTXCID101517326; Setmelanotide (RM-493); UNII-N7T15V1FUY; Setmelanotide [USAN:INN]; Setmelanotide [MI]; Setmelanotide [USAN]; SETMELANOTIDE [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Setmelanotide?

CAS 920014-72-8; molecular formula C49H68N18O9S2; molecular weight — g/mol.

What other names is Setmelanotide known by?

Setmelanotide, 920014-72-8, RM-493, BIM-22493, Setmelanotida, N7T15V1FUY.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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