Sodium 4-Phenylbutyrate

Description

Sodium 4-Phenylbutyrate · CAS 1716-12-7 · C10H11NaO2. UNII NT6K61736T.

Identification

Computed Descriptors

Regulatory Status

GHS Hazard Classification

Documented Uses

• Phenylbutyrate and sodium benzoate are orphan drugs approved for the treatment of hyperammonemia in patients with urea cycle disorders, a series of at least 8 rare genetic enzyme deficiencies. The urea cycle is the major pathway of elimination of excess nitrogen including ammonia, and absence of one of the urea cycle enzymes often causes elevations in serum ammonia which can be severe, life-threatening and result in permanent neurologic damage and cognitive deficiencies. Both phenylbutyrate and sodium benzoate act
• Breast Feeding; Lactation; Milk, Human; Urea Cycle Disorders
• Substances that inhibit or prevent the proliferation of NEOPLASMS.
• Ammonium Ion Binding Activity [MoA]; Nitrogen Binding Agent [EPC]
• SODIUM PHENYLBUTYRATE TABLETS, 500 MG
• A - Alimentary tract and metabolism

Synonyms

Sodium 4-phenylbutyrate; SODIUM PHENYLBUTYRATE; 1716-12-7; Buphenyl; TriButyrate; Benzenebutanoic acid, sodium salt; Ammonaps; Pheburane; 4-phenylbutyric acid, sodium salt; OLPRUVA; DTXSID7040948; NT6K61736T; ACER-001; NSC-657802; DTXCID5020948; CHEBI:75316

Frequently Asked Questions

What are the CAS number and molecular formula of Sodium 4-Phenylbutyrate?

CAS 1716-12-7; molecular formula C10H11NaO2; molecular weight — g/mol.

What other names is Sodium 4-Phenylbutyrate known by?

Sodium 4-phenylbutyrate, SODIUM PHENYLBUTYRATE, 1716-12-7, Buphenyl, TriButyrate, Benzenebutanoic acid, sodium salt.

Is Sodium 4-Phenylbutyrate classified as hazardous?

2.3% of GHS notifications report no hazard classification (1 of 44).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.