Sodium Butyrate

Description

Sodium Butyrate · CAS 156-54-7 · C4H7NaO2. UNII 8RAS91C36W. Density: 0.96 @25 °C; Vapor Pressure: 0.00000015 [mmHg].

Identification

CAS Registry Number	156-54-7
PubChem CID	5222465
Molecular formula	C4H7NaO2
IUPAC name	sodium butanoate
UNII (FDA)	8RAS91C36W

Computed Descriptors

Molecular Weight	110.09
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	110.03437374
Monoisotopic Mass	110.03437374
Topological Polar Surface Area	40.1
Heavy Atom Count	7
Formal Charge	0
Complexity	53.7

Physical & Chemical Properties

Density	0.96 @25 °C
Vapor Pressure	0.00000015 [mmHg]

Physical description & handling notes

• White powder; [MSDSonline]

GHS Hazard Classification

Reported hazard statements	H302 (16.7%), H315 (100%), H319 (100%), H335 (88.9%), H341 (33.3%)

Documented Uses

• Butanoic acid, sodium salt (1:1): ACTIVE
• Drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. Classical antihistaminics block the histamine H1 receptors only.
• SODIUM BUTYRATE INHIBITED INITIATION OF VIRAL AND CELLULAR DNA REPLICATION IN POLYOMA VIRUS-INFECTED MOUSE KIDNEY CELLS.
• 24 HR AFTER TREATMENT OF FRIEND ERYTHROLEUKEMIA CELLS WITH MILLIMOLAR CONCN OF SODIUM BUTYRATE, THE CHROMATIN HISTONES HAD BECOME HYPERACETYLATED. DURING THIS SAME TIME PERIOD, THE BUTYRATE-TREATED FRIEND CELLS ACCUMULATED A POPULATION OF APPROX 38% NEW RNA TRANSCRIPTS SYNTHESIZED FROM UNIQUE SEQUENCES OF MOUSE DNA.
• Sodium butyrate treatment enhanced the development of colonic neoplasia and was associated with increased fecal butyric acid concentrations in rats given parenteral administration of 1,2-dimethylhydrazine.
• Inhibitors of DNA polymerase efficiently inhibit initiator induced amplification of SV40 DNA sequences in the SV40 transformed Chinese hamster cell line CO631. Sodium butyrate inhibits DNA synthesis by histone modification.

Synonyms

SODIUM BUTYRATE; 156-54-7; Sodium butanoate; Butanoic acid, sodium salt; Butyric acid sodium salt; Butyrate sodium; Butyric acid, sodium salt; Sodium n-butyrate; Sodium propanecarboxylate; Sodium butyrate (USP); DTXSID3037672; 8RAS91C36W; Sodium butyrate [USP]; NSC-174280; DTXCID1017672; CHEBI:64103

Frequently Asked Questions

What are the CAS number and molecular formula of Sodium Butyrate?

CAS 156-54-7; molecular formula C4H7NaO2; molecular weight — g/mol.

What other names is Sodium Butyrate known by?

SODIUM BUTYRATE, 156-54-7, Sodium butanoate, Butanoic acid, sodium salt, Butyric acid sodium salt, Butyrate sodium.

Is Sodium Butyrate classified as hazardous?

Hazard statements reported: H302, H315, H319, H335, H341.

What are the key physical properties of Sodium Butyrate?

Density: 0.96 @25 °C; Vapor Pressure: 0.00000015 [mmHg].

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.