大豆异黄酮

Description

SOYBEAN ISOFLAVONE · CAS 574-12-9 · C15H10O2. UNII OVO2KUW8H8.

Identification

CAS Registry Number	574-12-9
PubChem CID	72304
Molecular formula	C15H10O2
IUPAC name	3-phenylchromen-4-one
UNII (FDA)	OVO2KUW8H8

Computed Descriptors

Molecular Weight	222.24
XLogP3	3.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	222.068079557
Monoisotopic Mass	222.068079557
Topological Polar Surface Area	26.3
Heavy Atom Count	17
Formal Charge	0

Regulatory Status

GHS notification summary	100% (52 / 52)

GHS Hazard Classification

GHS notification summary	100% (52 / 52)

Documented Uses

• Indicated for over-the-counter use as a dietary supplement for increasing bone density and regulating blood fat.
• Renal excretion is the predominant route of elimination for dietary isoflavones, where approximately 10-60% of total administered dose is excreted in urine. Glucuronide conjugates account for the majority (70-90%) of the isoflavone content in urine, followed by sulphate conjugates (10-25%) and aglycone forms (1-10%). Fecal excretion is minimal, which accounts for 1-4% of the dietary isoflavone ingested.
• Isoflavones are readily distributed to all tissues, and they are known to cross the placental barrier and blood brain barrier. They are also distributed to the extra-vascular compartments. In a human study, the volume of distribution of daidzein and genistein were 336.25 L and 258.76 L, respectively.
• In a human study, the clearance rate for daidzein and genistein were 30.09 L/h and 21.85 L/h, respectively.
• No pharmacokinetic data available.
• The half-life of isoflavones is between 4 and 8 h. Daidzein has a longer intestinal half-life than genistein due to more rapid degradation of genistein. Individual half-life of daidzein and genistein in a human pharmacokinetic study were 7.75 h and 7.77 h, respectively.

Synonyms

Isoflavone; 574-12-9; 3-Phenylchromone; 3-phenyl-4H-1-benzopyran-4-one; isoflavon; OVO2KUW8H8; NSC-135405; NSC135405; DTXSID90205986; CHEBI:18220; Homoisoflavone; Isoflavones; Isoflavone Derivative; Derivative, Isoflavone; 3 Benzylchroman 4 One; 3 Benzylchroman 4 Ones

Frequently Asked Questions

What are the CAS number and molecular formula of SOYBEAN ISOFLAVONE?

CAS 574-12-9; molecular formula C15H10O2; molecular weight — g/mol.

What other names is SOYBEAN ISOFLAVONE known by?

Isoflavone, 574-12-9, 3-Phenylchromone, 3-phenyl-4H-1-benzopyran-4-one, isoflavon, OVO2KUW8H8.

Is SOYBEAN ISOFLAVONE classified as hazardous?

100% of GHS notifications report no hazard classification (52 of 52).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.