Sulfapyridine

Description

Sulfapyridine · CAS 144-83-2 · C11H11N3O2S. UNII Y5V2N1KE8U. Melting Point: 376 to 379 °F (NTP, 1992); Melting Point: 192; Melting Point: 192 °C.

Identification

CAS Registry Number	144-83-2
PubChem CID	5336
Molecular formula	C11H11N3O2S
IUPAC name	4-amino-N-pyridin-2-ylbenzenesulfonamide
UNII (FDA)	Y5V2N1KE8U

Computed Descriptors

Molecular Weight	249.29
XLogP3	0
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	249.05719778
Monoisotopic Mass	249.05719778
Topological Polar Surface Area	93.5
Heavy Atom Count	17
Formal Charge	0

Physical & Chemical Properties

Melting Point	376 to 379 °F (NTP, 1992)
Melting Point	192
Melting Point	192 °C
Solubility	268
Solubility	2.35e-01 g/L
LogP	0.35
LogP	0.9
Dissociation Constants	8.43
Collision Cross Section	152.7 Ų [M+H]+
Collision Cross Section	156.54 Ų [M-H]-

Physical description & handling notes

• Sulfapyridine appears as odorless or almost odorless white or yellowish-white crystalline powder. Very slightly bitter taste. Aqueous solution is neutral. (NTP, 1992)
• Solid
• less than 1 mg/mL at 72 °F (NTP, 1992)
• 33.1 [ug/mL] (The mean of the results at pH 7.4)
• 158.33 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 150.94 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	12% (6 / 50)

GHS Hazard Classification

GHS notification summary	12% (6 / 50)
Reported hazard statements	H300 (72%), H317 (72%), H360 (72%), H361 (12%), H370 (72%), H411 (72%)

Documented Uses

• Use (kg) in Switzerland (2009): >1000
• Use (kg; approx.) in Germany (2009): >25000
• Use (kg; exact) in Germany (2009): 33245
• Consumption (g per capita) in Switzerland (2009): 0.13
• Consumption (g per capita; approx.) in Germany (2009): 0.31
• Consumption (g per capita; exact) in Germany (2009): 0.41

Synonyms

sulfapyridine; 144-83-2; Sulphapyridine; 2-Sulfapyridine; 2-Sulfanilamidopyridine; Dagenan; Piridazol; Sulfidin; Sulfidine; Streptosilpyridine; Coccoclase; Plurazol; Pyriamid; Pyridazol; Eubasin; 2-Sulfanilylaminopyridine

Frequently Asked Questions

What are the CAS number and molecular formula of Sulfapyridine?

CAS 144-83-2; molecular formula C11H11N3O2S; molecular weight — g/mol.

What other names is Sulfapyridine known by?

sulfapyridine, 144-83-2, Sulphapyridine, 2-Sulfapyridine, 2-Sulfanilamidopyridine, Dagenan.

Is Sulfapyridine classified as hazardous?

12% of GHS notifications report no hazard classification (6 of 50).

What are the key physical properties of Sulfapyridine?

Melting Point: 376 to 379 °F (NTP, 1992); Melting Point: 192; Melting Point: 192 °C; Solubility: 268.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.