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Description

Sulpiride · CAS 15676-16-1 · C15H23N3O4S. UNII 7MNE9M8287. Melting Point: 178; Melting Point: 178 °C; Solubility: 5.37e-01 g/L.

Identification

CAS Registry Number	15676-16-1
PubChem CID	5355
Molecular formula	C15H23N3O4S
IUPAC name	N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
UNII (FDA)	7MNE9M8287

Computed Descriptors

Molecular Weight	341.4
XLogP3	0.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	341.14092740
Monoisotopic Mass	341.14092740
Topological Polar Surface Area	110
Heavy Atom Count	23
Formal Charge	0

Physical & Chemical Properties

Melting Point	178
Melting Point	178 °C
Solubility	5.37e-01 g/L
LogP	0.57
LogP	0.6
LogP	1.56
Dissociation Constants	9.12

Physical description & handling notes

• Solid
• >51.2 [ug/mL] (The mean of the results at pH 7.4)
• 186.0 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID1042574]
• 192.2 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID1042574]
• 185.3 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID1042574]
• 184.9 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated]

Regulatory Status

GHS notification summary	57.1% (4 / 7)

GHS Hazard Classification

GHS notification summary	57.1% (4 / 7)
Reported hazard statements	H302, H312, H332 (14.3%), H361 (28.6%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >2500
• Consumption (g per capita; approx.) in Germany (2009): 0.0305
• Sulpiride is indicated for the treatment of acute and chronic schizophrenia.
• Breast Feeding; Lactation; Milk, Human; Antipsychotic Agents; Dopamine Antagonists
• Avoid alcohol. Alcohol enhances the sedative effects of sulpiride.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.

Synonyms

sulpiride; 15676-16-1; Sulpyrid; Sulpirid; Aiglonyl; Dogmatil; Dogmatyl; Dolmatil; Abilit; Guastil; Coolspan; Mirbanil; Misulvan; Neogama; Omperan; Splotin

Frequently Asked Questions

What are the CAS number and molecular formula of Sulpiride?

CAS 15676-16-1; molecular formula C15H23N3O4S; molecular weight — g/mol.

What other names is Sulpiride known by?

sulpiride, 15676-16-1, Sulpyrid, Sulpirid, Aiglonyl, Dogmatil.

Is Sulpiride classified as hazardous?

57.1% of GHS notifications report no hazard classification (4 of 7).

What are the key physical properties of Sulpiride?

Melting Point: 178; Melting Point: 178 °C; Solubility: 5.37e-01 g/L; LogP: 0.57.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.