他扎罗汀

Description

Tazarotene · CAS 118292-40-3 · C21H21NO2S. UNII 81BDR9Y8PS. Solubility: 7.50e-04 g/L; LogP: 5.6.

Identification

CAS Registry Number	118292-40-3
PubChem CID	5381
Molecular formula	C21H21NO2S
IUPAC name	ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate
UNII (FDA)	81BDR9Y8PS

Computed Descriptors

Molecular Weight	351.5
XLogP3	4.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	351.12930009
Monoisotopic Mass	351.12930009
Topological Polar Surface Area	64.5
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Solubility	7.50e-04 g/L
LogP	5.6

Physical description & handling notes

• Solid
• Soluble

Documented Uses

• Used to treat psoriasis, acne and sun damaged skin (photodamage).
• Breast Feeding; Lactation; Milk, Human; Dermatologic Agents; Keratolytic Agents
• Drugs used to treat or prevent skin disorders or for the routine care of skin.
• Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
• An agent that causes the production of physical defects in the developing embryo.
• Established Pharmacologic Class [EPC] - Retinoid

Synonyms

tazarotene; 118292-40-3; Tazorac; Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate; Zorac; Avage; AGN-190168; Fabior; tazaroteno; tazarotenum; DTXSID5046691; Idp-123; 81BDR9Y8PS; AGN190168; ARAZLO; DUOBRII COMPONENT TAZAROTENE

Frequently Asked Questions

What are the CAS number and molecular formula of Tazarotene?

CAS 118292-40-3; molecular formula C21H21NO2S; molecular weight — g/mol.

What other names is Tazarotene known by?

tazarotene, 118292-40-3, Tazorac, Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate, Zorac, Avage.

What are the key physical properties of Tazarotene?

Solubility: 7.50e-04 g/L; LogP: 5.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.