Tepotinib

Name: Tepotinib
Brand: Jinan Shenghe Chemical Co., Ltd.

CAS 1100598-32-0C29H28N6O2MW 492.6

Tepotinib (CAS No. 1100598-32-0) is supplied by Jinan Shenghe Chemical Co., Ltd. with a typical purity of 按批次COA提供(不公开发布). Main applications include Organic Chemicals. Bulk quantities are available with COA; purity and packaging are subject to batch COA and order confirmation.

Specifications

CAS Number1100598-32-0

Molecular FormulaC29H28N6O2

Molecular Weight492.6

LogP3.4

Purity按批次COA提供(不公开发布)

Packaging按订单/批次确认(不公开发布)

ApplicationsOrganic Chemicals

CategoryOrganic Chemicals

Where it is used

Organic Chemicals

Packaging & Supply

Packaging按订单/批次确认(不公开发布)

Purity按批次COA提供(不公开发布)

StorageSealed, cool and dry place

Lead TimeIn stock / per order

Documents & Support

COA provided with every batch; MSDS and technical documents available on request. Email us with product name and CAS number for a quote within one business day.

Frequently Asked Questions

What is the CAS number of Tepotinib?

The CAS number of Tepotinib is 1100598-32-0.

What purity and packaging are available?

Typical purity is 按批次COA提供(不公开发布), supplied in 按订单/批次确认(不公开发布), with COA provided.

What are the applications of Tepotinib?

Main applications include Organic Chemicals.

How do I buy Tepotinib or get a quote?

Email info@591daili.com or reach us on WhatsApp with the product name, CAS number and required quantity; quotes within one business day. Supplier: Jinan Shenghe Chemical Co., Ltd..

PubChem Public Data

Description

Tepotinib · CAS 1100598-32-0 · C29H28N6O2. UNII 1IJV77EI07. Dissociation Constants: 9.5.

Identification

CAS Registry Number	1100598-32-0
PubChem CID	25171648
Molecular formula	C29H28N6O2
IUPAC name	3-[1-[[3-[5-[(1-methylpiperidin-4-yl)methoxy]pyrimidin-2-yl]phenyl]methyl]-6-oxopyridazin-3-yl]benzonitrile
UNII (FDA)	1IJV77EI07

Computed Descriptors

Molecular Weight	492.6
XLogP3	3.4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	492.22737416
Monoisotopic Mass	492.22737416
Topological Polar Surface Area	94.7
Heavy Atom Count	37
Formal Charge	0

Physical & Chemical Properties

Dissociation Constants	9.5

Documented Uses

Tepotinib is indicated for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) who have mesenchymal-epithelial transition (_MET_) exon 14 skipping alterations.
Tepotinib is an orally available, small molecule inhibitor of the mesenchymal-epithelial transition (MET) factor tyrosine kinase receptor that is used to treat selected cases of non-small cell lung cancer (NSCLC). Serum aminotransferase elevations are common during therapy with tepotinib, but it has not been linked to instances of clinically apparent liver injury with jaundice.
Breast Feeding; Lactation; Antineoplastic Agents; Enzyme Inhibitors; Protein Kinase Inhibitors; Tyrosine Kinase Inhibitors
Take with food. Co-administration with a meal improves the absorption of tepotinib.
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Established Pharmacologic Class [EPC] - Kinase Inhibitor

Synonyms

Tepotinib; 1100598-32-0; EMD-1214063; EMD 1214063; EMD1214063; MSC2156119J; MSC-2156119J; MSC2156119; MSC-2156119; 1IJV77EI07; DTXSID70149132; tepotinibum; RefChem:57995; DTXCID0071623; c-Met Inhibitor MSC2156119J; Tepotinib [INN]

Frequently Asked Questions

What are the CAS number and molecular formula of Tepotinib?

CAS 1100598-32-0; molecular formula C29H28N6O2; molecular weight — g/mol.

What other names is Tepotinib known by?

Tepotinib, 1100598-32-0, EMD-1214063, EMD 1214063, EMD1214063, MSC2156119J.

What are the key physical properties of Tepotinib?

Dissociation Constants: 9.5.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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