特立帕肽

Description

Teriparatide · CAS 52232-67-4 · C181H291N55O51S2. UNII 10T9CSU89I.

Identification

CAS Registry Number	52232-67-4
PubChem CID	16133850
Molecular formula	C181H291N55O51S2
UNII (FDA)	10T9CSU89I

Computed Descriptors

Molecular Weight	4118
XLogP3	-18.7
Hydrogen Bond Donor Count	60
Hydrogen Bond Acceptor Count	62
Rotatable Bond Count	146
Exact Mass	4116.1342973
Monoisotopic Mass	4115.1309424
Topological Polar Surface Area	1800
Heavy Atom Count	289
Formal Charge	0

Physical description & handling notes

• Parenteral: Injection: 750 ug/3 mL (20 ug per metered dose/pen device), Forteo (available as prefilled disposable cartridge), (Lilly).

GHS Hazard Classification

Reported hazard statements	H302 (16.7%), H332 (16.7%), H351 (50%), H361 (100%), H372 (33.3%), H373 (16.7%), H336, H350

Documented Uses

• Stimulates new bone formation on trabecular and cortical (periosteal and/or endosteal) bone surfaces by preferential stimulation of osteoblastic activity over osteoclastic activity.
• Bone Density Conservation Agents
• Manufactured using a strain of Escherichia coli modified by recombinant DNA technology
• Teriparatide is a recombinant human parathyroid hormone analogue that is used to treat osteoporosis in women or men with a high risk for bone fracture. Teriparatide therapy has not been associated with serum aminotransferase elevations during therapy and has not been implicated in instances of clinically apparent liver injury.
• Breast Feeding; Lactation; Milk, Human; Parathyroid Hormone; Calcium-Regulating Hormones and Agents; Bone Density Conservation Agents
• Teriparatide (genetical recombination)

Synonyms

TERIPARATIDE; 52232-67-4; Teriparatida; Teriparatidum; 1-34-Human PTH; Human PTH (1-34); ZT-034; LY 333334; 10T9CSU89I; TERIPARATIDE RECOMBINANT HUMAN; hPTH (1-34); BONSITY; RefChem:56774; H05AA02; DTXSID001027900; Teriparatide (genetical recombination)

Frequently Asked Questions

What are the CAS number and molecular formula of Teriparatide?

CAS 52232-67-4; molecular formula C181H291N55O51S2; molecular weight — g/mol.

What other names is Teriparatide known by?

TERIPARATIDE, 52232-67-4, Teriparatida, Teriparatidum, 1-34-Human PTH, Human PTH (1-34).

Is Teriparatide classified as hazardous?

Hazard statements reported: H302, H332, H351, H361, H372.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.