丙酸睾酮

Description

Testosterone Propionate · CAS 57-85-2 · C22H32O3. UNII WI93Z9138A. Melting Point: 244 to 252 °F (NTP, 1992); Melting Point: 118-123 °C; Solubility: 1.48.

Identification

CAS Registry Number	57-85-2
PubChem CID	5995
Molecular formula	C22H32O3
IUPAC name	[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate
UNII (FDA)	WI93Z9138A

Computed Descriptors

Molecular Weight	344.5
XLogP3	4.4
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	344.23514488
Monoisotopic Mass	344.23514488
Topological Polar Surface Area	43.4
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Melting Point	244 to 252 °F (NTP, 1992)
Melting Point	118-123 °C
Solubility	1.48
Solubility	5.02e-03 g/L
LogP	3.72

Physical description & handling notes

• Testosterone propionate appears as odorless white or yellowish-white crystals or a white or creamy-white crystalline powder. (NTP, 1992)
• Solid
• less than 1 mg/mL at 76.1 °F (NTP, 1992)
• 191.1 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID9036515]
• 188.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• The administration of testosterone propionate can induce production of proteins related to male sexual development. Clinical trials have shown a decrease in plasma LH after the administration of testosterone propionate.

GHS Hazard Classification

Reported hazard statements	H302 (96.6%), H350 (65.5%), H351 (32.2%), H360 (51.7%), H361 (44.8%), H362 (27.6%), H373 (20.7%), H411 (19.5%)

Documented Uses

• Testosterone propionate is an anabolic steroid and a short ester form of testosterone that becomes active in the body. It is often used for muscle mass building.
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17.beta.)-: INACTIVE
• Testosterone propionate is used in veterinary practice in heifers in order to stimulate maximal growth.
• Testosterone propionate presents a slow absorption from the intramuscular site of administration. This slow absorption is due to the presence of the less polar ester group. The absorption rate of testosterone propionate generates a frequent injection requirement when compared with testosterone enanthate or testosterone cypionate. It presents absorption parameters of AUC and residence time of 180-210 ng h/ml and 40-60 h, respectively.
• About 90% of a dose of testosterone given intramuscularly is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites. From the rest of the dose, approximately 6% of a dose is excreted in the feces, mostly in the unconjugated form.

Synonyms

testosterone propionate; 57-85-2; Bio-testiculina; Enarmon; Androtest P; Androlon; Androteston; Aquaviron; Hormoteston; Testodet; Testodrin; Testogen; Testonique; Testormol; Testrex; Tostrin

Frequently Asked Questions

What are the CAS number and molecular formula of Testosterone Propionate?

CAS 57-85-2; molecular formula C22H32O3; molecular weight — g/mol.

What other names is Testosterone Propionate known by?

testosterone propionate, 57-85-2, Bio-testiculina, Enarmon, Androtest P, Androlon.

Is Testosterone Propionate classified as hazardous?

Hazard statements reported: H302, H350, H351, H360, H361.

What are the key physical properties of Testosterone Propionate?

Melting Point: 244 to 252 °F (NTP, 1992); Melting Point: 118-123 °C; Solubility: 1.48; Solubility: 5.02e-03 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.