Tetraethylene glycol

Description

Tetraethylene glycol · CAS 25322-68-3 · C2H6O2. UNII FC72KVT52F. Boiling Point: 387.7 °F at 760 mmHg (NTP, 1992); Boiling Point: 197.3 °C; Boiling Point: 197.00 to 198.00 °C. @ 760.00 mm Hg.

Identification

CAS Registry Number	25322-68-3
PubChem CID	174
Molecular formula	C2H6O2
IUPAC name	ethane-1,2-diol
UNII (FDA)	FC72KVT52F

Computed Descriptors

Molecular Weight	62.07
XLogP3	-1.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	62.036779430
Monoisotopic Mass	62.036779430
Topological Polar Surface Area	40.5
Heavy Atom Count	4
Formal Charge	0

Physical & Chemical Properties

Boiling Point	387.7 °F at 760 mmHg (NTP, 1992)
Boiling Point	197.3 °C
Boiling Point	197.00 to 198.00 °C. @ 760.00 mm Hg
Boiling Point	197 °C
Boiling Point	388 °F
Boiling Point	197.3 °C @760 [mm Hg]
Melting Point	9 °F (NTP, 1992)
Melting Point	-12.69 °C
Melting Point	4 - 10 °C
Melting Point	-13 °C

Physical description & handling notes

• Ethylene glycol is a clear, colorless syrupy liquid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Since it is a liquid it can easily penetrate the soil and contaminate groundwater and nearby streams.
• CBI; Other Solid; Liquid
• PEG 400 is a clear, viscous, colourless or almost colourless hygroscopic liquid; PEG 3000, PEG 3350, PEG 4000, PEG 6000 and PEG 8000 are white or almost white solids with a waxy or paraffin-like appearance
• Clear, colorless, syrupy, odorless liquid. [antifreeze] [Note: A solid below 9 degrees F.]; [NIOSH]
• Liquid
• ODOURLESS COLOURLESS VISCOUS HYGROSCOPIC LIQUID.

Regulatory Status

Regulatory & Food Contact	FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS ADJUVANT; CARRIER_SOLVENT: Food Additives Addition polymers of ethylene oxide and water usually designated by a number roughly corresponding to the mole MACROGOL JECFA ADI: 0-10 mg/kg bw
GHS notification summary	0.1% (3 / 8196)

GHS Hazard Classification

GHS notification summary	0.1% (3 / 8196)
Reported hazard statements	H302, H373 (24.8%), H315, H320, H332, H335, H336, H370

Documented Uses

• CIR ingredient: Ethylene Glycol
• Ethylene glycol is used as antifreeze in cooling and heating systems, in hydraulic brake fluids, as an industrial humectant, as an ingredient of electrolytic condensers, as a solvent in the paint and plastics industries, in the formulations of printers' inks, stamp pad inks, and inks for ballpoint pens, as a softening agent for cellophane, and in the synthesis of safety explosives, plasticizers, synthetic fibers (Terylene, Dacron), and synthetic waxes.
• Used in antifreeze and deicing solutions for cars, boats, and aircraft; also used as a solvent for paints, plastics, photographic developing solutions, coolants, hydraulic fluids, and inks; [ATSDR ToxFAQs] Highest risk for exposure in deicing aircraft and runways; [Reference #2] Occupational exposure mainly through skin and eyes, but also inhalation if heated or aerosolized; 50% solution used to de-ice bridges; Has been used in adhesives, polishes, cosmetics, and pharmaceuticals; [ACGIH]
• Painting (Solvents) [Category: Paint]
• Working with Glues and Adhesives [Category: Other]
• Photographic Processing [Category: Other]

Synonyms

ETHYLENE GLYCOL; Ethane-1,2-diol; 107-21-1; 1,2-ethanediol; glycol; monoethylene glycol; 2-hydroxyethanol; 1,2-Dihydroxyethane; Glycol alcohol; Ethylene alcohol; Fridex; Tescol; Norkool; Ethylene dihydrate; Zerex; ethanediol

Frequently Asked Questions

What are the CAS number and molecular formula of Tetraethylene glycol?

CAS 25322-68-3; molecular formula C2H6O2; molecular weight — g/mol.

What other names is Tetraethylene glycol known by?

ETHYLENE GLYCOL, Ethane-1,2-diol, 107-21-1, 1,2-ethanediol, glycol, monoethylene glycol.

What is the regulatory status of Tetraethylene glycol?

Documented regulatory listings: FDA Cumulative Estimated Daily Intake (CEDI): FCS; FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS; ADJUVANT; CARRIER_SOLVENT: Food Additives.

Is Tetraethylene glycol classified as hazardous?

0.1% of GHS notifications report no hazard classification (3 of 8196).

What are the key physical properties of Tetraethylene glycol?

Boiling Point: 387.7 °F at 760 mmHg (NTP, 1992); Boiling Point: 197.3 °C; Boiling Point: 197.00 to 198.00 °C. @ 760.00 mm Hg; Boiling Point: 197 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.